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Evidence for genetic variation of Eurasian avian influenza viruses of subtype H15: the first report of an H15N7 virus

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Abstract

Since the first detection of H15 avian influenza viruses (AIVs) in Australia in 1979, only seven H15 strains have been reported. A new H15 AIV was detected in Ukraine in 2010, carrying the unique HA-NA subtype combination H15N7. This virus replicated efficiently in chicken eggs, and antisera against it reacted strongly with the homologous antigen, but with lower titers when using the reference Australian antigen. The amino acid motifs of the HA cleavage site and receptor-binding site were different from those in the Australian viruses. The new virus, together with an H15 virus from Siberia from 2008, constitutes a new clade of H15 AIV isolates.

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Acknowledgments

The authors gratefully acknowledge Tina Seehafer for the technical assistance, and the ornithologists from Azov-Black Sea Ornithological Station, especially Dr. R.M. Chernychko, for identification of birds’ species and providing information on biological and ecological characteristics of wild birds from the Azov-Black Sea region of Ukraine. This research was funded partially by USDA project P444, through the Ukrainian Science and Technology Center.

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Author notes

  1. Sasan Fereidouni

    Present address: University of Veterinary Medicine Vienna, Research Institute of Wildlife Ecology, Vienna, Austria

Authors and Affiliations

  1. National Scientific Center, Institute of Experimental and Clinical Veterinary Medicine, Kharkiv, Ukraine

    Denys Muzyka

  2. Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, GA, USA

    Mary Pantin-Jackwood

  3. Friedrich Loeffler Institute, Greifswald, Insel Riems, Germany

    Elke Starick & Sasan Fereidouni

  4. WESCA Wildlife Network, Greifswald, Germany

    Sasan Fereidouni

Authors
  1. Denys Muzyka
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  2. Mary Pantin-Jackwood
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  3. Elke Starick
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  4. Sasan Fereidouni
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Corresponding author

Correspondence to Sasan Fereidouni.

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Muzyka, D., Pantin-Jackwood, M., Starick, E. et al. Evidence for genetic variation of Eurasian avian influenza viruses of subtype H15: the first report of an H15N7 virus. Arch Virol 161, 605–612 (2016). https://doi.org/10.1007/s00705-015-2629-2

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  • DOI: https://doi.org/10.1007/s00705-015-2629-2

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