Abstract
Background
To investigate the long-term stability and possible cataractogenesis after femtosecond laser treatment of the crystalline lens.
Methods
The crystalline lenses of ten Göttingen minipigs® underwent femtosecond laser treatment. During a subsequent 1-year follow-up, the pigs were monitored by means of slit-lamp examination of the anterior segment and Scheimpflug imaging of the lens.
Results
No laser-induced cataractogenesis was observed during the 1-year follow-up. The laser pattern showed a stable appearance under all examination devices.
Conclusion
Femtosecond laser treatment seems to be no trigger for cataract formation. Moreover, the long-term stability of the laser pattern makes it suitable for applications such as presbyopia treatment.
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Acknowledgement
This work is supported by the German Federal Ministry of Education and Research (Grant-IDs: 13 N8831, 13 N8835). We are also grateful to Dr. Matthias Reich for his assistance during the preparation of this study.
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None of the authors have any financial or proprietary interest in any material or method mentioned. The authors declare that they have full control of all primary data. They agree to allow Graefe’s Archive for Clinical and Experimental Ophthalmology to review their data upon request.
Parts of the content were presented as posters at the Annual Meeting 2010 of the Association for Research in Vision and Ophthalmology (ARVO) and the 5th European Meeting on Visual and Physiological Optics (EMVPO) 2010.
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Ackermann, R., Kunert, K.S., Kammel, R. et al. Femtosecond laser treatment of the crystalline lens: a 1-year study of possible cataractogenesis in minipigs. Graefes Arch Clin Exp Ophthalmol 249, 1567–1573 (2011). https://doi.org/10.1007/s00417-011-1772-z
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DOI: https://doi.org/10.1007/s00417-011-1772-z