Lung

, Volume 191, Issue 4, pp 441–443

Interstitial Lung Disease in a Child with Antisynthetase Syndrome

  • Don HayesJr.
  • Peter B. Baker
  • Heidi M. Mansour
  • Mark E. Peeples
  • Kathleen K. Nicol
Article

DOI: 10.1007/s00408-013-9468-2

Cite this article as:
Hayes, D., Baker, P.B., Mansour, H.M. et al. Lung (2013) 191: 441. doi:10.1007/s00408-013-9468-2

Abstract

Introduction

Antisynthetase Syndrome is associated with interstitial lung disease in adult patients, but this has not been described in children.

Materials and methods

A 13-year-old with interstitial lung disease due to Antisynthetase Syndrome and pulmonary arterial hypertension underwent emergent bilateral lung transplantation after a rapid clinical decline.

Conclusion

We present the clinical, radiographic, and histological findings of a child with interstitial lung disease due to Antisynthetase Syndrome.

Keywords

Antisynthetase syndromeAnti-Jo-1 antibodyChildInterstitial lung disease

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Don HayesJr.
    • 1
  • Peter B. Baker
    • 2
  • Heidi M. Mansour
    • 3
  • Mark E. Peeples
    • 1
  • Kathleen K. Nicol
    • 2
  1. 1.Department of PediatricsThe Ohio State University College of Medicine, Nationwide Children’s HospitalColumbusUSA
  2. 2.Department of PathologyThe Ohio State University College of Medicine, Nationwide Children’s HospitalColumbusUSA
  3. 3.Department of Pharmaceutical SciencesUniversity of Kentucky College of PharmacyLexingtonUSA