European Archives of Oto-Rhino-Laryngology

, Volume 265, Issue 10, pp 1219-1223

First online:

The effects of spirulina on allergic rhinitis

  • Cemal CingiAffiliated withDepartment of of ENT, Eskisehir Osmangazi University Medical Faculty Email author 
  • , Meltem Conk-DalayAffiliated withDepartment of Bioengineering, Ege University, Engineering Faculty
  • , Hamdi CakliAffiliated withDepartment of of ENT, Eskisehir Osmangazi University Medical Faculty
  • , Cengiz BalAffiliated withDepartment of Biostatistics, Eskisehir Osmangazi University Medical Faculty

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The prevalence of allergic rhinitis is increasing globally due to various causes. It affects the quality life of a large group of people in all around the world. Allergic rhinitis still remains inadequately controlled with present medical means. The need of continuous medical therapy makes individuals anxious about the side effects of the drugs. So there is a need for an alternative strategy. Effects of spirulina, tinospora cordifolia and butterbur were investigated recently on allergic rhinitis in just very few investigations. Spirulina represents a blue-green alga that is produced and commercialized as a dietary supplement for modulating immune functions, as well as ameliorating a variety of diseases. This double blind, placebo controlled study, evaluated the effectiveness and tolerability of spirulina for treating patients with allergic rhinitis. Spirulina consumption significantly improved the symptoms and physical findings compared with placebo (P < 0.001***) including nasal discharge, sneezing, nasal congestion and itching. Spirulina is clinically effective on allergic rhinitis when compared with placebo. Further studies should be performed in order to clarify the mechanism of this effect.


Allergic rhinitis Spirulina Blue-green alga Nasal discharge Nasal congestion