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CT fluoroscopy-guided lung biopsy versus conventional CT-guided lung biopsy: a prospective controlled study to assess radiation doses and diagnostic performance

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Abstract

Objective

We evaluated radiation doses, complication rates, and diagnostic accuracy for CT-guided percutaneous needle aspiration biopsy (NAB) procedures of pulmonary lesions performed with or without fluoroscopic guidance.

Methods

A total of 142 patients were prospectively enrolled to receive CT-guided NAB with (Group I, n = 72) or without (Group II, n = 70) fluoroscopic guidance. Outcome measurements were patient and doctor radiation dose, and complication rate. Sensitivity, specificity and accuracy were calculated based on 123 NAB results.

Results

The mean estimated effective patient radiation dose was 6.53 mSv in Group I and 2.72 mSv in Group II (p < 0.001). The mean estimated effective doctor dose was 0.054 mSv in Group I and 0.029 mSv in Group II (p < 0.001). The complication rate was significantly different between the two groups (13.4% versus 31.4%, p = 0.012). Sensitivity, specificity and accuracy for diagnosing pulmonary lesions were 97.8%, 100% and 98.4% in group I and 95.3%, 100% and 89.5% in group II (p > 0.05).

Conclusions

CT fluoroscopy-guided NAB of pulmonary lesions provides high diagnostic accuracy and can be performed with significantly fewer complications. However, radiation exposure to both patient and doctor were significantly higher than conventional CT-guided NAB.

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Authors and Affiliations

  1. Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul, South Korea

    Ga Ram Kim, Sang Min Lee, Hye-Jeong Lee, Yoo Jin Hong, Ji Eun Nam, Hua Sun Kim, Young Jin Kim, Byoung Wook Choi, Tae Hoon Kim & Kyu Ok Choe

  2. Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, 250 Seongsanno (134 Sinchon-dong), Seodaemun-gu, Seoul, 120-752, South Korea

    Jin Hur

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  1. Ga Ram Kim
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  2. Jin Hur
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  3. Sang Min Lee
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  4. Hye-Jeong Lee
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  7. Hua Sun Kim
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Correspondence to Jin Hur.

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Kim, G.R., Hur, J., Lee, S.M. et al. CT fluoroscopy-guided lung biopsy versus conventional CT-guided lung biopsy: a prospective controlled study to assess radiation doses and diagnostic performance. Eur Radiol 21, 232–239 (2011). https://doi.org/10.1007/s00330-010-1936-y

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  • DOI: https://doi.org/10.1007/s00330-010-1936-y

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