Abstract.
Nitrile-converting enzymes are becoming commonplace in the synthesis of pharmaceuticals and commodity chemicals. These versatile biocatalysts have potential applications in different fields including synthetic biocatalysis and bioremediation. This review attempts to describe in detail the three major classes of nitrile-converting enzymes, namely nitrilases, nitrile hydratases and amidases. Various aspects of these enzymes including their occurrence, mechanism of action, characteristics and applicability in different sectors have been elaborately elucidated. Cloning of genes related to nitrile-converting enzymes is also discussed.
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The article has been retracted at the request of the Editor-in-Chief, as it contains portions of other authors' writings on the same topic in other publications, without sufficient attribution to these earlier works being given. The principal authors of the paper acknowledged that text from background sources was mistakenly used in this article without proper reference to the original source.
An erratum to this article is available at http://dx.doi.org/10.1007/s00253-016-7708-0.
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Banerjee, A., Sharma, R. & Banerjee, U. RETRACTED ARTICLE: The nitrile-degrading enzymes: current status and future prospects. Appl Microbiol Biotechnol 60, 33–44 (2002). https://doi.org/10.1007/s00253-002-1062-0
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DOI: https://doi.org/10.1007/s00253-002-1062-0