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Mechanismen der Kontrolle des Tonus der glatten Muskulatur der Prostata und ihre potentielle Bedeutung für die Pharmakotherapie des benignen Prostatasyndroms

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Literatur

  1. Becker AJ, Stief CG, Meyer M et al. (1998) The effects of the specific phosphodiesterase 4 inhibitor rolipram on the ureteral peristalsis of the rabbit in vitro and in vivo. J Urol 160: 920–925

    Article  PubMed  CAS  Google Scholar 

  2. Truss MC, Stief CG, Ückert S et al. (2000) Initial clinical experience with the selective phosphodiesterase (PDE) 1 isoenzyme inhibitor vinpocetine in the treatment of urge incontinence and low compliance bladder. World J Urol 18: 439–443

    Article  PubMed  CAS  Google Scholar 

  3. McMahon CG, Stuckey BG, Andersen M et al. (2005) Efficacy of sildenafil citrate (Viagra) in men with premature ejaculation. J Sex Med 2: 368–375

    Article  PubMed  CAS  Google Scholar 

  4. Ückert S, Mayer ME, Jonas U, Stief CG (2006) Potential future options in the pharmacotherapy of female sexual dysfunction. World J Urol 24: 630–638

    Article  PubMed  Google Scholar 

  5. Mulhall JP, Guhring P, Parker M, Hopps CJ (2006) Assessment of the impact of sildenafil citrate on lower urinary tract symptoms in men with erectile dysfunction. J Sex Med 3: 662–667

    Article  PubMed  CAS  Google Scholar 

  6. Gonzalez RR, Kaplan SA (2006) Tadalafil for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia. Expert Opin Drug Metab Toxicol 2: 609–617

    Article  PubMed  CAS  Google Scholar 

  7. Langenstroer P, Tang R, Shapiro E et al. (1993) Endothelin-1 in the human prostate: tissue levels, source of production and isometric tension studies. J Urol 149: 495–499

    Google Scholar 

  8. Hiraoka Y, Oshita M, Morikawa K et al. (2000) Characterization of endothelin receptor subtypes in human prostate. J Cardiovasc Pharmacol 36(Suppl 1): 252–254

    Google Scholar 

  9. Corvin S, Bösch St, Eder I et al. (1998) Videoimaging of prostatic stromal cell contraction: an in vitro model for studying drug effects. Prostate 37: 209–214

    Article  PubMed  CAS  Google Scholar 

  10. Kedia G, Truss MC, Chigogidze T et al. (2006) Nitric oxide donors reverse the tension induced by ET-1 of isolated human prostate tissue and stimulate the production of cyclic GMP. Eur Urol 5(2 Suppl): 122

    Google Scholar 

  11. Kedia G, Sormes M, Ückert S et al. (2007) Contraction – relaxation studies on isolated human prostate tissue: the role of endothelin 1, phosphodiesterase inhibitors and cyclic nucleotides. Eur Urol 6(2 Suppl): 34

    Google Scholar 

  12. Heuer O, Ückert S, Dobler G et al. (2004) Effects of phosphodiesterase inhibitors and nitric oxide donors on cultured human prostatic smooth muscle cells. Eur Urol 3(2 Suppl): 19

    Google Scholar 

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Correspondence to U. Jonas.

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Ückert, S., Kedia, G., Klocker, H. et al. Mechanismen der Kontrolle des Tonus der glatten Muskulatur der Prostata und ihre potentielle Bedeutung für die Pharmakotherapie des benignen Prostatasyndroms. Urologe 46, 1187–1188 (2007). https://doi.org/10.1007/s00120-007-1424-4

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