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Besonderheiten der abdominellen Sepsis

Special aspects of abdominal sepsis

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Zusammenfassung

Die abdominelle Sepsis stellt nach wie vor eine Hauptursache postoperativer Morbidität und Mortalität dar. Sie ist eine Erkrankung, die grundsätzlich als lebensbedrohlich einzuschätzen ist und immer eine intensivmedizinische Behandlung erfordert. Neben der lokalen Infektion der Bauchhöhle im Sinne einer Peritonitis treten bei der abdominellen Sepsis extraperitoneale Allgemeinreaktionen auf. Diese können bei Fortschreiten der Erkrankung zum septischen Multiorganversagen und letztlich zum Tod des Patienten führen. Die kausale Therapie besteht weiterhin in einer frühzeitigen chirurgischen oder interventionellen Herdsanierung sowie in einer zunächst breiten, später gezielten antimikrobiellen Behandlung.

Abstract

Abdominal sepsis remains a major cause of perioperative morbidity and mortality in surgical intensive care units. It must be considered a life-threatening condition and requires multidisciplinary coordination of intensive care. Apart from the local abdominal infection (peritonitis), abdominal sepsis is defined by extraperitoneal systemic reactions potentially leading to septic shock and death in the further course. Early and radical focus sanitation as well as aggressive systemic antimicrobial therapy remain the causal therapy strategies of abdominal sepsis.

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Danksagung

Diese Arbeit wurde unterstützt vom Graduiertenkolleg 840 der Deutschen Forschungsgemeinschaft (DFG): „Wechselwirkungen zwischen Erreger und Wirt bei generalisierten bakteriellen Infektionen“ und vom Bundesministerium für Bildung und Forschung (NBL3 Programm, ref. 01 ZZ 0103).

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Authors and Affiliations

  1. Klinik und Poliklinik für Chirurgie, Ernst-Moritz-Arndt-Universität Greifswald

    S. Maier, T. Traeger, A. Westerholt &  C.-D. Heidecke

  2. Klinik und Poliklinik für Chirurgie, Ernst-Moritz-Arndt-Universität Greifswald, Friedrich-Loeffler-Straße 23b, 17487 , Greifswald

    C.-D. Heidecke

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  1. S. Maier
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  2. T. Traeger
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  3. A. Westerholt
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  4. C.-D. Heidecke
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Correspondence to C.-D. Heidecke.

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Maier, S., Traeger, T., Westerholt, A. et al. Besonderheiten der abdominellen Sepsis. Chirurg 76, 829–836 (2005). https://doi.org/10.1007/s00104-005-1066-2

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  • DOI: https://doi.org/10.1007/s00104-005-1066-2

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