Skip to main content
SpringerLink
Log in

ESR study on scavenging effect of nicotine on free radicals

  • Published:
Applied Magnetic Resonance Aims and scope Submit manuscript

Abstract

Smokers have less risk to catch degenerative diseases such as Alzheimer’s disease and Parkinson’s disease that are both correlated with enhanced oxidative stress. The scavenging effect of nicotine on free radicals was investigated by electron spin resonance techniques. It was found that the scavenging effect of nicotine on hydroxyl radicals and superoxide free radicals was higher than that of vitamin C. It was also found that nicotine could scavenge free radicals in gas-phase cigarette smoke. The data indicate that nicotine may be a potential antioxidant.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Irfan R., William M.N.: Free Radic. Biol. Med.21, 669–681 (1996)

    Article  Google Scholar 

  2. William A.P.: Environ. Health Perspect.105, 875–882 (1997)

    Article  Google Scholar 

  3. Morens D.M., Grandinetti A., Reed D., White L.R., Ross G.W.: Neurology45, 1041–1051 (1995)

    Google Scholar 

  4. Soto-Otero S., Mendez-Alvarez E., Riguera-Vega R., Quinoa-Cabana E., Sanchez-Sellero I., Lamas M.L.: Brain Res.802, 155–162 (1995)

    Article  Google Scholar 

  5. Brenner D.E., Kukull W.A., van Belle G., Bowen J.B., McCormic W.C., Teri L., Larson E.B.: Neurology43, 293–300 (1993)

    Google Scholar 

  6. Ulrich J., Johannson-Locher G., Seiler W.O., Stahelin H.B.: Acta Neuropathol.94, 450–454 (1997)

    Article  Google Scholar 

  7. Hillier V., Salib E.: Int. J. Geriatr. Psychiatry12, 295–300 (1997)

    Article  Google Scholar 

  8. Levin E.D., Christopher N.C., Briggs S.J., Auman J.T.: Drug Dev. Res.39, 29–35 (1996)

    Article  Google Scholar 

  9. Levin E.D., Briggs S.J., Christopher N.C., Rose J.E.: Behav. Pharmacol.4, 179–182 (1993)

    Article  Google Scholar 

  10. Amir H.R., Edward D.L.: Biol. Psychiatry49, 258–267 (2001)

    Article  Google Scholar 

  11. Samuels S.C., Davis K.L.: Harv. Rev. Psychiatry6, 11–22 (1998)

    Article  Google Scholar 

  12. Wonnacott S.: Trends Neurosci.20, 92–98 (1997)

    Article  Google Scholar 

  13. Church D.F., Pryor W.A.: Environ. Health Perspect.64, 111–126 (1985)

    Article  Google Scholar 

  14. Zhao B.L., Yan L.J., Hou J.W., Xin W.J.: Natl. Med. J. China70, 387–391 (1990)

    Google Scholar 

  15. Ludwig P.W., Hoidal J.R.: Am. Rev. Respir. Dis.126, 977–980 (1982)

    Google Scholar 

  16. Hoidal J.R., Fox R.B., Lemarbe P.A., Perri R., Repine J.E.: Am. Rev. Respir. Dis.123, 85–89 (1981)

    Google Scholar 

  17. Halliwell B., Gutteridge J.M.C. (eds.): Free Radicals in Biology and Medicine, pp. 416–508. Oxford: Clarendon Press 1989.

    Google Scholar 

  18. Olanow C.W., Arendash G.W.: Curr. Opin. Neurol.7, 548–558 (1994)

    Article  Google Scholar 

  19. Linert W., Bridge M.H., Huber M., Bjugstad K.B., Grossman S., Arendash G.W.: Biochim. Biophys. Acta1454, 143–152 (1999)

    Google Scholar 

  20. Cassarino, David S., Fall, Christopher P., Swerdlow R.H., Smith T.S., Halvorson E.M., Miller S.W., Parks J.P., Parker W.D., Bennertt J.P.: Biochim. Biophys. Acta1362, 77–86 (1997)

    Google Scholar 

  21. Zhao B.I., Li X.J., Liu G.T., Xin W.J.: Cell Biol. Int. Rep.13, 529–534 (1989)

    Article  Google Scholar 

  22. Pryor W.A., Lightsey J.W.: Science214, 435–439 (1981)

    Article  ADS  Google Scholar 

  23. Patel J.M., Block E.R.: Free Radic. Biol. Med.4, 121–134 (1988)

    Article  Google Scholar 

  24. Stähelin H.B.: Eur. Psychiatry13, 169 (1998)

    Article  Google Scholar 

  25. Behl C.: Prog. Neurobiol.57, 301–323 (1999)

    Article  Google Scholar 

  26. Deibel M.A., Ehmann W.D. Markesbery W.R.: J. Neurol. Sci.143, 137–142 (1996)

    Article  Google Scholar 

  27. Ihara T., Yuetsu Y., Chuda N., Masaki M., Kuroda H., Shigetoshi T., Hayabara S., Toshiyuki K.: J. Neurol. Sci.170, 90–95 (1999)

    Article  Google Scholar 

  28. Naoi H., Makoto S., Maruyama A., Wakako K.: Mech. Ageing Dev.111, 175–188 (1999)

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Visual Information Processing, Center of Brain and Cognitive Science, Institute of Biophysics, Academia Sinica, 100101, Beijing, People’s Republic of China

    Q. Liu, Y. Tao & B. Zhao

Authors
  1. Q. Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Y. Tao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. B. Zhao
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Liu, Q., Tao, Y. & Zhao, B. ESR study on scavenging effect of nicotine on free radicals. Appl. Magn. Reson. 24, 105–112 (2003). https://doi.org/10.1007/BF03166682

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03166682

Keywords

Search

Navigation