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Treatment consideration and manifest complexity in comorbid neuropsychiatric disorders

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Abstract

Psychiatric disorders may co-occur in the same individual. These include, for example, substance abuse or obsessive-compulsive disorder with schizophrenia, and movement disorders or epilepsy with affective dysfunctional states. Medications may produce iatrogenic effects, for example cognitive impairments that co-occur with the residual symptoms of the primary disorder being treated. The observation of comorbid disorders in some cases may reflect diagnostic overlap. Impulsivity, impulsiveness or impulsive behaviour is implicated in a range of diagnostic conditions including substance abuse, affective disorder and obsessive-compulsive disorder. These observations suggest a need to re-evaluate established diagnostic criteria and disorder definitions, focusing instead on symptoms and symptom-profiles.

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Authors and Affiliations

  1. Psychiatry Service, “12 de Octubre”, University Hospital, 28041, Madrid, Spain

    Tomas Palomo

  2. Department of Pharmacology, Quillen College of Medicine, East Tennessee State University, 37614, Johnson City, TN, USA

    Richard M. Kostrzewa

  3. Departments of Psychology and Psychiatry, Queen’s University, K7L 3N6, Kingston, ON, Canada

    Richard J. Beninger

  4. Department of Psychology, University of Göteborg, Box 500, SE-45030, Göteborg

    Trevor Archer

  5. HBV, University of Kalmar, SE-39182, Kalmar, Sweden

    Trevor Archer

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Palomo, T., Kostrzewa, R.M., Beninger, R.J. et al. Treatment consideration and manifest complexity in comorbid neuropsychiatric disorders. neurotox res 12, 43–60 (2007). https://doi.org/10.1007/BF03033900

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