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Synthesis of Mannich bases of Antineoplaston A10 and their antitumor activity

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Abstract

Some Mannich bases of Antineoplaston A10 which is antitumor agent under clinical investigation were synthesized and tested for cytotoxicity. The tested compounds (2a, 2b, 2d) showed good activity comparable to that of carboplatin.

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Choi, BG., Seo, HK., Chung, BH. et al. Synthesis of Mannich bases of Antineoplaston A10 and their antitumor activity. Arch. Pharm. Res. 17, 467–469 (1994). https://doi.org/10.1007/BF02979127

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  • DOI: https://doi.org/10.1007/BF02979127

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