Abstract
3-(1,1-Dioxadibenzothien-4-oyl)acrylic acid (1) was condensed with compounds containing active methylene groups under Michael reaction conditions to furnish the Michael adducts (lactones,2a–c, lactams,3a–c, ketones4a, b). The behavior of these adducts toward the action of hydrazine hydrate were investigated. The compounds were tested for their biological properties.
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1st part of this series:Egypt. J. Chem. 42, 309 (1999).
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Wasfy, A.A.F., Amine, M.S., Arief, M.M.H. et al. α,β-unsaturated 4-oxo acids in heterocyclic synthesis. Folia Microbiol 47, 131–136 (2002). https://doi.org/10.1007/BF02817670
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DOI: https://doi.org/10.1007/BF02817670