Summary
This work is devoted to the study of the role of the antibodies in induction of immunity to Brown-Pearce carcinoma. Serum or splenic tissue and lymph node tissue, obtained from rabbits immune to the tumor was introduced to rabbits. The subsequent inoculation of the tumor tissue to experimental animals was connected in a number of cases with complete or partial inhibition of the tumor growth. These data demonstrate the significance of the antibodies in the mechanism of antitumor protection of the organism.
Similar content being viewed by others
Literature Cited
A.A. Bogomolets, Vrachebnoe Delo 8, 562–566 (1938).
V.D. Vinogradov, Experimental Study of Specific and Nonspecific Resistance to Malignant Tumors (Experimental Investigation Using Artificial Immunization of White Mice), Candidate's Dissertation. (Moscow, 1948). In Russian.
R. E. Kavetskii and M.P. Fediushin, Transactions of the 1st Congress of Oncologists of the Ukrainian SSR, 1940, pp. 374–377.
M.S. Lomakin, Biull. Eksptl. Biol. i Med. 9, 40–44 (1956). Original Russian pagination. See C.B. translation.
P.P. Filatov, Biull. Eksptl. Biol. i Med. 11, 56 (1955).
A. Besredka and L. Gross, Wien. med. Wschr. 86, 509–514 (1936).
J. Bichel and I. Holm-Jensen, Acta path. a. microbiol. Scand. 26, 319–322 (1949).
J.S. Colter, H.H. Bird, H. Koprowski et al., Nature 177, 4517, 993–994 (1956).
G. Damagk, Ztschr. f. Krebsforsch. 56, 247–252 (1949).
A.D. Dulaney and K. Arnesen, Proc. Soc. Exper. Biol. and Med. 72, 665–668 (1949).
N.G. Falls and A. Kirschbaum, Proc. Am. Assoc. Cancer Research 1, 15 (1953).
P.A. Gorer, Ann. New York Acad. Sci. 1, 15 (1956).
P.A. Gorer and D.B. Amos, Cancer Research 16, 338–343 (1956).
J.G. Kidd, J. Exper. Med. 83, 227–240 (1946).
T. Lumsden, Lancet, 1, 116–122 (1927); Am. J. Cancer 15, 563–640 (1931); 31, 430–440 (1937).
D.G. Millet, J. Nat. Cancer Inst. 16, 1473–1484 (1956).
A. Nettleship. Am. J. of Pathol. 21, 527–541 (1945).
H.J. Phelps. Am. J. Cancer 31, 441–445 (1937).
R. Schreck and F.W. Preston, J. Nat. Cancer Inst. 16, 1021–1033 (1956).
A.C. Snell and B.V. Favate, Cancer Research 11, 335–340 (1951).
J.E. Todd and J.G. Kidd, Proc. Soc. Exper. Biol. and Med. 86, 865–868 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Radzikhovskaia, R.M. An experimental study of the role of antibodies in immunity to tumors. Bull Exp Biol Med 45, 609–613 (1958). https://doi.org/10.1007/BF00784980
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00784980