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Toxicokinetic study of rat intestinal brush border membrane enzymes following in vitro exposure to lead and vanadium

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References

  • Boelsterli U, Zbinden G (1979) Application of fine needle aspiration biopsy for the diagnosis of dysplastic and neoplastic liver cell changes induced by N-nitrosomorpholine in rats. Arch Toxicol 42:225–233.

    Google Scholar 

  • Bond GH, Hudgins PM (1980) Inhibition of red cell Ca+2-ATPase by vanadate. Biochim Biophys Acta 600:781–790.

    Google Scholar 

  • Cantley LC (Jr), Cantley LG, Hosephson L (1978) A characterization of vanadate interactions with (Na+ +K+)ATPase, mechanistic and regulatory implication. J Biol Chem 253:7361–7368.

    Google Scholar 

  • Dahlqvist A (1964) Methods for the assay of intestinal disaccharidases. Anal Biochem 7:18–25.

    Google Scholar 

  • Dixon M (1953) Determination of enzyme inhibitor constants. Biochem J 55:170–171.

    Google Scholar 

  • Dux L, Martonosi A (1983) Ca+2-ATPase crystals in sarcoplasmic reticulum: Effect of trypsin digestion. J Biol Chem 258:10111–10115.

    Google Scholar 

  • Forstner GG, Sebesin SM, Isselbacker KJ (1968) Rat intestinal microvillus membranes. Biochem J 106:381–390.

    Google Scholar 

  • Goldstein GW, Ar D(1983) Lead activated calmodulin sensitive processes. Life Sci 33:101–106.

    Google Scholar 

  • Haffar JJ, Rowe NA, Tomicic TK (1988) The non specific nature of the vanadate inhibition of rat ileal Na+-K+-ATPase. Life Sci 43:1741–1746.

    Google Scholar 

  • Hestrin S (1949) Reaction of acetylcholine and other carboxylic acid derivatives with hydroxylamine. J Biol Chem 180:249–261.

    Google Scholar 

  • Hidalgo C, Gonzalez ME, Logos R (1983) Characterization of Ca+2 or Mg+2-ATPase of transverse tubule membranes isolated from rabbit skeletal muscle. J Biol Chem 258:13937–13945.

    Google Scholar 

  • Holtzman D, Hus JS, Mortell P (1978) In vitro effects of inorganic lead on isolated rat brain mitochondrial respiration. Neurochem Res 3:195–200.

    Google Scholar 

  • Jandhyala RS, Hom GJ (1983) Physiological and pharmacological properties of vanadium. Life Sci 33:1325–1340.

    Google Scholar 

  • Klip A, Grinstein S, Semenza G (1979) Transmembrane disposition of the phlorizin binding protein of intestinal brush border. FEBS Lett 99:91–96.

    Google Scholar 

  • Kuliszewska KT, Nicholis DM (1985) Rat kidney brush border enzyme activity following subchronic oral exposure. Toxicol Appl Pharmacol 77:211–218.

    Google Scholar 

  • Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with folin phenol reagent J Biol Chem 193:265–275.

    CAS  PubMed  Google Scholar 

  • Nordberg GF (1976) In: Effect and dose response relationship of toxic metals. Elsevier Scientific Pub. Co. New York: p15.

    Google Scholar 

  • Pirkle JL, Shwartz J, Landis JR, Harlen WR (1985) The relationship between blood lead level and blood presure and its cardiovascular risk implications. Amer J Epidemiol 121:246–258.

    Google Scholar 

  • Siegel, GJ, Fogt SK (1977) Inhibition by lead ion of electrophorus Na+ -K+ -adenosine triphosphatase and K+-p-nitrophenyl phosphatase. J Biol Chem 252:5201–5205.

    Google Scholar 

  • Weiser MM (1973) Intestinal cell surface membrane glycoprotein synthesis — An indicator of cellular differentiation. J Biol Chem 248:2536–2541.

    Google Scholar 

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Authors and Affiliations

  1. Biomembrane Laboratory, Industrial Toxicology Research Centre, Post Box No. 80, 226 001, Lucknow, India

    K. Gupta, R. K. Upreti & A. M. Kidwai

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  1. K. Gupta
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  2. R. K. Upreti
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  3. A. M. Kidwai
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Gupta, K., Upreti, R.K. & Kidwai, A.M. Toxicokinetic study of rat intestinal brush border membrane enzymes following in vitro exposure to lead and vanadium. Bull. Environ. Contam. Toxicol. 52, 919–926 (1994). https://doi.org/10.1007/BF00200703

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  • DOI: https://doi.org/10.1007/BF00200703

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