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1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase

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Abstract

Acyl carrier proteins participate in the synthesis of fatty acids. Here we report the NMR resonances assignment of the acyl carrier protein domain of the Saccharomyces cerevisiae fatty acid synthase which corresponds to the fragment 138A-302L in the primary structure. The assignment will allow performing NMR studies with the aim to investigate the intrinsic dynamics of this protein, and to study the structural changes upon apo-holo transformation in order to unveil the mechanism of binding of the growing acyl chain.

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Acknowledgments

This work was supported by the Swiss National Science Foundation (SNF) project number 3100A0-113730.

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Authors and Affiliations

  1. Institute of Molecular Biology and Biophysics, ETH Zurich, 8093, Zurich, Switzerland

    Daniel R. Perez & Gerhard Wider

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  1. Daniel R. Perez
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  2. Gerhard Wider
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Correspondence to Gerhard Wider.

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Perez, D.R., Wider, G. 1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase. Biomol NMR Assign 3, 133–136 (2009). https://doi.org/10.1007/s12104-009-9158-4

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