Skip to main content

Advertisement

Log in

Successful treatment of lung adenocarcinoma in an 18-year-old man

  • Case Report
  • Published:
General Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Primary lung cancer is an extremely rare neoplasm in young adults. We report a case of a primary lung adenocarcinoma in an 18-year-old man who presented for examination of a solitary nodule located in the right lower lobe of the lung. A right lower lobectomy was performed with an incomplete resection because of pleural dissemination (pT4N2M0 stage IIIB adenocarcinoma). Intrathoracic chemotherapy (cisplatin, 50 mg/body) was administered initially, followed by systemic chemotherapy (carboplatin + paclitaxel). A bronchopleural fistula occurred 2 months postoperatively and was successfully treated with conservative therapy, including thoracic drainage, intrathoracic fibrin glue administration, and transbronchial superglue administration. Thereafter, a total of five courses of systemic chemotherapy with minor changes in the administration regimen were performed. The patient was alive and with no evidence of recurrence at his 5-year follow-up.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Mery CM, Pappas AN, Bueno R, Colson YL, Linden P, Sugarbaker DJ, et al. Similar long-term survival of elderly patients with non-small cell lung cancer treated with lobectomy or wedge resection within the surveillance, epidemiology, and end results database. Chest 2005;128:237–245.

    Article  PubMed  Google Scholar 

  2. Japanese Joint Committee for Lung Cancer Registration. A Japanese lung cancer registry study at 1999. Jpn J Chest Surg 2007;21:108–120.

    Google Scholar 

  3. Mountain CF, Dresler CM. Regional lymph node classification for lung cancer staging. Chest 1997;111:1718–1723.

    Article  CAS  PubMed  Google Scholar 

  4. Seto T, Ushijima S, Yamamoto H, Ito K, Araki J, Inoue Y, et al. Thoracic Oncology Group. Intrapleural hypotonic cisplatin treatment for malignant pleural effusion in 80 patients with non-small-cell lung cancer: a multi-institutional phase II trial. Br J Cancer 2006;95:717–721.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Sugaya M, Sugio K, Nagashima A, Nakanishi R, Sakata H, Nakanishi K, et al. Phase II trial of adjuvant chemotherapy with bi-weekly carboplatin plus paclitaxel in patients with completely resected non-small cell lung cancer. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 23:7258.

  6. Bryant A, Cerfolio RJ. Differences in epidemiology, histology, and survival between cigarette smokers and never-smokers who develop non-small cell lung cancer. Chest 2007;132:185–192.

    Article  PubMed  Google Scholar 

  7. Sirbu H, Busch T, Aleksic I, Schreiner W, Oster O, Dalichau H. Bronchopleural fistula in the surgery of non-small cell lung cancer: incidence, risk factors, and management. Ann Thorac Cardiovasc Surg 2001;7:330–336.

    CAS  PubMed  Google Scholar 

  8. Kirsh MM, Rotman H, Behrendt DM, Orringer MB, Sloan H. Complications of pulmonary resection. Ann Thorac Surg 1975;20:215–236

    Article  CAS  PubMed  Google Scholar 

  9. Oyama T, Fujimoto H, Suito T, Takahashi Y, Fukutomi T, Naruke M. Successful conservative therapy for bronchopleural fistula after primary lung cancer resection. Jpn J Chest Surg 2010;24:18–23.

    Article  Google Scholar 

  10. The Japan Lung Cancer Society. Evidence-based guidelines for treatment of lung cancer in Japan: 2005 edition. Tokyo: Japan Lung Cancer Society; 2005.

    Google Scholar 

  11. Rosell R, Moran T, Queralt C, Porta R, Cardenal F, Camps C, et al. Spanish Lung Cancer Group. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009;361:958–967.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tetsuya So.

Rights and permissions

Reprints and permissions

About this article

Cite this article

So, T., Uramoto, H., Hanagiri, T. et al. Successful treatment of lung adenocarcinoma in an 18-year-old man. Gen Thorac Cardiovasc Surg 59, 616–618 (2011). https://doi.org/10.1007/s11748-010-0730-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11748-010-0730-8

Key words

Navigation