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Pregnancy Following Gastric Bypass for Morbid Obesity: Effect of Surgery-to-Conception Interval on Maternal and Neonatal Outcomes

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Abstract

Background

Conception is discouraged during the period of maximal weight loss following Roux-en-Y gastric bypass (RYGB) because of speculative maternal and fetal concerns. We therefore performed a retrospective cohort study of obstetrical and neonatal outcomes by surgery-to-conception interval.

Methods

Women with RYGB were stratified into two groups by surgery-to-conception interval of ≤18 or >18 months. Pregnancy and newborn outcomes excluding miscarriages were compared using the chi-square or unpaired t-test for dichotomous and continuous variables, respectively.

Results

Twenty subjects conceived ≤18 months (11.4 ± 5.0) and 32 conceived >18 months (47.5 ± 41) after RYGB, p < .05. Maternal age, parity, body mass index, and weight gain were similar by group. There were no statistically significant differences in adverse obstetrical outcomes (preterm premature membrane rupture, gestational diabetes, oligohydramnios, intrauterine growth restriction, preterm or post-term delivery) or adverse newborn outcomes (5-min Apgar score < 7, intensive care admission, or birth defect).

Conclusion

Obstetrical and neonatal outcomes are similar in women conceiving during or after the period of maximal weight loss following RYGB.

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References

  1. National Center for Health Statistics. Health, United States, 2006 with chartbook on trends in the health of Americans. Hyattsville, MD;2006.

  2. Wax JR, Pinette MG, Cartin A, et al. Female reproductive issues following bariatric surgery. Obstet Gynecol Survey. 2007;62:595–604.

    Article  Google Scholar 

  3. Teitelman M, Grotegut CA, Williams NN, et al. The impact of bariatric surgery on menstrual patterns. Obes Surg. 2006;16:1457–63.

    Article  PubMed  Google Scholar 

  4. Eid GM, Cottam DR, Velcu LM, et al. Effective treatment of polycystic ovarian syndrome with Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2005;1:77–80.

    Article  PubMed  Google Scholar 

  5. Deitel M, Stone E, Kassam HA, Wilk EJ, et al. Gynecologic–obstetric changes after loss of massive excess weight following bariatric surgery. J Am Coll Nutr. 1988;7:147–53.

    PubMed  CAS  Google Scholar 

  6. Bilenka B, Ben-Shlomo I, Cozacov C, et al. Fertility, miscarriage, and pregnancy after vertical banded gastroplasty operation for morbid obesity. Acta Obstet Gynecol Scand. 1995;74:42–4.

    Article  PubMed  CAS  Google Scholar 

  7. American College of Obstetricians and Gynecologists. ACOG Committee Opinion 315: Obesity in pregnancy. Obstet Gynecol. 2005;106:671–5.

    Google Scholar 

  8. Wittgrove AC, Jester L, Wittgrove P, et al. Pregnancy following gastric bypass for morbid obesity. Obes Surg. 1998;8:461–4.

    Article  PubMed  CAS  Google Scholar 

  9. Rand CW, Macgregor AM. Medical care and pregnancy outcome after gastric bypass surgery for obesity. South Med J. 1989;82:1319–20.

    PubMed  CAS  Google Scholar 

  10. Dao T, Kuhn J, Ehmer D, et al. Pregnancy outcomes after gastric-bypass surgery. Am J Surg. 2006;192:762–6.

    Article  PubMed  Google Scholar 

  11. Patel JA, Patel NA, Thomas RL, et al. Pregnancy outcomes after laparoscopic Roux-en-Y gastric bypass. Surg Obes Relat Dis. 2008;4:39–45.

    Article  PubMed  Google Scholar 

  12. Wax JR, Cartin A, Wolff R, et al. Pregnancy following gastric bypass for morbid obesity: maternal and neonatal outcomes. Obes Surg. 2008;18:540–4.

    Article  PubMed  Google Scholar 

  13. Haddow JE, Hill LE, Kloza EM, et al. Neural tube defects after gastric bypass. Lancet. 1986;1:1330.

    Article  PubMed  CAS  Google Scholar 

  14. Printen KJ, Scott D. Pregnancy following gastric bypass for the treatment of morbid obesity. Am Surg. 1982;48:363–5.

    PubMed  CAS  Google Scholar 

  15. Martin JA, Hamilton BE, Sutton PD, et al. Births: Final data for 2005. National Vital Statistics Reports. Dec 5, 2007. Vol 36, No. 6.

  16. Ananth CV, Joseph KS, Oyelese Y, et al. Trends in preterm birth and perinatal mortality among singletons: United States, 1989 through 2000. Obstet Gynecol. 2005;105:1084–91.

    PubMed  Google Scholar 

Download references

Acknowledgment

The authors thank F. Lee Lucas, Ph.D. for performing the statistical analyses.

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Authors and Affiliations

  1. Division of Maternal–Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, ME, 04102, USA

    Joseph R. Wax, Angelina Cartin, Michael G. Pinette & Jacquelyn Blackstone

  2. Maine Bariatric Surgery Program, Department of Surgery, Maine Medical Center, Portland, ME, USA

    Renee Wolff & Sharon Lepich

  3. MMC Ob/Gyn Associates, 887 Congress Street, Suite 200, Portland, ME, 04102, USA

    Joseph R. Wax

Authors
  1. Joseph R. Wax
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  2. Angelina Cartin
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  3. Renee Wolff
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  4. Sharon Lepich
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  5. Michael G. Pinette
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  6. Jacquelyn Blackstone
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Correspondence to Joseph R. Wax.

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Wax, J.R., Cartin, A., Wolff, R. et al. Pregnancy Following Gastric Bypass for Morbid Obesity: Effect of Surgery-to-Conception Interval on Maternal and Neonatal Outcomes. OBES SURG 18, 1517–1521 (2008). https://doi.org/10.1007/s11695-008-9647-z

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  • DOI: https://doi.org/10.1007/s11695-008-9647-z

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