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Absorbable Mesh Reinforcement of a Stapled Pancreatic Transection Line Reduces the Leak Rate with Distal Pancreatectomy

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Pancreatic leak remains a significant cause of morbidity after distal pancreatectomy. We report the use of an absorbable mesh to reinforce a stapled pancreatic transection line for distal pancreatectomy. Forty consecutive distal pancreatectomies (33 open and 7 laparoscopic) were performed since the introduction of mesh reinforcement. We utilized an inclusive definition of pancreatic leak to critically evaluate the staple line reinforcement material. In addition, we compared the pancreatic leak rate for this case series with the antecedent 40 cases where mesh reinforcement was not available. In the prospective series there was 1 leak in 29 cases (3.5%) in which mesh reinforcement was utilized, and 4 leaks in 11 cases (36%) when mesh was not utilized (p < 0.005). The 12.5% leak rate for the 40 cases during the prospective period, compared favorably to the 27.5% leak rate for the 40 cases preceding the study period (p = 0.09). Twenty-nine cases receiving mesh compared favorably to the 23 stapled cases in the control series, reducing leak rate from 22 to 3.5% (p = 0.04). Mesh reinforcement of the stapled pancreatic transection line reduced the pancreatic leak rate after distal pancreatectomy. Mesh reinforcement was possible with open or laparoscopic resections. No complications were attributable to the use of absorbable mesh.

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Acknowledgments

We wish to acknowledge the National Institute of Health, Kirstein Surgical Research Scholarship Program for the scholarship award, and Timothy J. Eberlein, M.D. of Washington University School of Medicine.

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Authors and Affiliations

  1. Department of Surgery, Division of Hepatobiliary, Pancreatic, and Gastrointestinal Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8109, St Louis, MO, 63110, USA

    Reuben I. Thaker, Brent D. Matthews, David C. Linehan, Steven M. Strasberg, J. Chris Eagon & William G. Hawkins

  2. Siteman Cancer Center, St. Louis, MO, USA

    David C. Linehan, Steven M. Strasberg & William G. Hawkins

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  1. Reuben I. Thaker
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  2. Brent D. Matthews
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  3. David C. Linehan
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  4. Steven M. Strasberg
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  5. J. Chris Eagon
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  6. William G. Hawkins
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Correspondence to William G. Hawkins.

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Thaker, R.I., Matthews, B.D., Linehan, D.C. et al. Absorbable Mesh Reinforcement of a Stapled Pancreatic Transection Line Reduces the Leak Rate with Distal Pancreatectomy. J Gastrointest Surg 11, 59–65 (2007). https://doi.org/10.1007/s11605-006-0042-6

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  • DOI: https://doi.org/10.1007/s11605-006-0042-6

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