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A distinctive translocation carcinoma of the kidney [“rosette-like forming,” t(6;11), HMB45-positive renal tumor]

  • Urology - Original Paper
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Abstract

Objective

Recently, a novel renal carcinoma with specific clinical and histological characteristics and translocation t(6;11)(p21.1;q12 or q13) has been identified. We have found 11 cases in the literature, and we are adding another 3 cases.

Materials and methods

Three cases were found in the Plzeň pathological register with approximately 15,000 cases of kidney tumors. There were two females and 1 male, aged 22, 24, and 39 years.

Results

The sizes of the tumors were 40, 136, and 10 mm. Two tumors were found incidentally; the biggest one was self-palpated by a 24-year-old pregnant patient. Patients are without any signs of disease 42, 20, and 17 months after surgery.

Conclusion

This tumor is a distinctive and rare translocation carcinoma of the kidney [t(6;11), HMB45 positive]. All cases with known clinical data arose in younger people. The malignant potential is probably low.

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Authors and Affiliations

  1. Department of Urology, Charles University Hospital, E. Beneše 13, 305 99, Plzen, Czech Republic

    Milan Hora, Tomáš Ürge, Viktor Eret & Jiří Klečka

  2. Department of Pathology, Charles University Hospital, Plzen, Czech Republic

    Ondřej Hes & Michal Michal

Authors
  1. Milan Hora
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  2. Ondřej Hes
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  3. Tomáš Ürge
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  4. Viktor Eret
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  5. Jiří Klečka
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  6. Michal Michal
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Corresponding author

Correspondence to Milan Hora.

Additional information

The work was supported by Czech government research project MSM 0021620819.

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Hora, M., Hes, O., Ürge, T. et al. A distinctive translocation carcinoma of the kidney [“rosette-like forming,” t(6;11), HMB45-positive renal tumor]. Int Urol Nephrol 41, 553–557 (2009). https://doi.org/10.1007/s11255-008-9495-8

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  • DOI: https://doi.org/10.1007/s11255-008-9495-8

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