Abstract
Rothia aeria caused a necrotic lymphadenitis and neck abscess in a patient with CGD. This infection was aggressive, crossed tissue planes, required two surgeries, as well as prolonged antibiotics for complete resolution. Rothia aeria is a rare pathogen that can be added to the spectrum of agents causing disease in CGD, a finding that further reinforces the importance of microbiologic identification of infections in this patient population.
References
Kuhns DB, Alvord WG, Heller T, Feld JJ, Pike KM, Marciano BE, et al. Residual NADPH oxidase and survival in chronic granulomatous disease. N Engl J Med. 2010;363:2600–10.
Towbin AJ, Chaves I. Chronic granulomatous disease. Pediatr Radiol. 2010;40:657–68. quiz 792-653.
Greenberg DE, Shoffner AR, Zelazny AM, Fenster ME, Zarember KA, Stock F, et al. Recurrent Granulibacter bethesdensis infections and chronic granulomatous disease. Emerg Infect Dis. 2010;16:1341–8.
Sugui JA, Vinh DC, Nardone G, Shea YR, Chang YC, Zelazny AM, et al. Neosartorya udagawae (Aspergillus udagawae), an emerging agent of aspergillosis: how different is it from Aspergillus fumigatus? J Clin Microbiol. 2010;48:220–8.
Falcone EL, Hanses S, Stock F, Holland SM, Zelazny AM, Uzel G. Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature. J Clin Immunol 2012.
Li Y, Kawamura Y, Fujiwara N, Naka T, Liu H, Huang X, et al. Rothia aeria sp. nov., Rhodococcus baikonurensis sp. nov. and Arthrobacter russicus sp. nov., isolated from air in the Russian space laboratory Mir. Int J Syst Evol Microbiol. 2004;54:827–35.
Boudewijns M, Magerman K, Verhaegen J, Debrock G, Peetermans WE, Donkersloot P, et al. Rothia dentocariosa, endocarditis and mycotic aneurysms: case report and review of the literature. Clin Microbiol Infection: Off Publ Eur Soc Clin Microbiol Infectious Dis. 2003;9:222–9.
Salamon SA, Prag J. Three cases of Rothia dentocariosa bacteraemia: frequency in Denmark and a review. Scand J Infect Dis. 2002;34:153–7.
Ergin C, Sezer MT, Agalar C, Katirci S, Demirdal T, Yayli G. A case of peritonitis due to Rothia dentocariosa in a CAPD patient. Peritoneal Dialysis Int: J Int Soc Peritoneal Dialysis. 2000;20:242–3.
Bousquet A, Soler C, Martinaud C, Join-Lambert O, Malfuson JV. Pneumonia and Rothia dentocariosa. Med Mal Infect. 2011;41:621–2.
Favero M, Raffeiner B, Cecchin D, Schiavon F. Septic arthritis caused by Rothia dentocariosa in a patient with rheumatoid arthritis receiving etanercept therapy. J Rheumatol. 2009;36:2846–7.
Morley AM, Tuft SJ. Rothia dentocariosa isolated from a corneal ulcer. Cornea. 2006;25:1128–9.
MacKinnon MM, Amezaga MR, MacKinnon JR. A case of Rothia dentocariosa endophthalmitis. Eur J Clin Microb Infectious Dis: Off Publ Eur Soc Clin Microbiol. 2001;20:756–7.
Morgan EA, Henrich TJ, Jarell AD, Shieh WJ, Zaki SR, Marty FM, et al. Infectious granulomatous dermatitis associated with Rothia mucilaginosa bacteremia: A case report. Am J Dermatopathol. 2010;32:175–9.
Hodzic E, Snyder S. A case of peritonitis due to Rothia mucilaginosa. Peritoneal Dialysis Int: J Int Soc Peritoneal Dialysis. 2010;30:379–80.
Lee AB, Harker-Murray P, Ferrieri P, Schleiss MR, Tolar J. Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation. Pediatric Blood Cancer. 2008;50:673–6.
Fusconi M, Conti C, De Virgilio A, de Vincentiis M. Paucisymptomatic pneumonia due to Rothia mucilaginosa: case report and literature review. Le Infezioni Med: Riv Period di Eziol, Epidemiol, Diagnostica, Clin Terapia Patologie Infettive. 2009;17:100–4.
Kaasch AJ, Saxler G, Seifert H. Septic arthritis due to Rothia mucilaginosa. Infection. 2011;39:81–2.
Verrall AJ, Robinson PC, Tan CE, Mackie WG, Blackmore TK. Rothia aeria as a cause of sepsis in a native joint. J Clin Microbiol. 2010;48:2648–50.
Michon J, Jeulin D, Lang JM, Cattoir V. Rothia aeria acute bronchitis: the first reported case. Infection. 2010;38:335–7.
Hiyamuta H, Tsuruta N, Matsuyama T, Satake M, Ohkusu K, Higuchi K. [First case report of respiratory infection with Rothia aeria]. Nihon Kokyuki Gakkai Zasshi = J Jpn Respir Soc. 2010;48:219–23.
Monju A, Shimizu N, Yamamoto M, Oda K, Kawamoto Y, Ohkusu K. First case report of sepsis due to Rothia aeria in a neonate. J Clin Microbiol. 2009;47:1605–6.
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This work was supported by the Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892. The views expressed in this article are those of the authors and do not reflect the official policy of the U.S. Government.
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Falcone, E.L., Zelazny, A.M. & Holland, S.M. Rothia aeria Neck Abscess in A Patient with Chronic Granulomatous Disease: Case Report and Brief Review of the Literature. J Clin Immunol 32, 1400–1403 (2012). https://doi.org/10.1007/s10875-012-9726-8
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DOI: https://doi.org/10.1007/s10875-012-9726-8