Skip to main content

Advertisement

Log in

Rothia aeria Neck Abscess in A Patient with Chronic Granulomatous Disease: Case Report and Brief Review of the Literature

  • Published:
Journal of Clinical Immunology Aims and scope Submit manuscript

Abstract

Rothia aeria caused a necrotic lymphadenitis and neck abscess in a patient with CGD. This infection was aggressive, crossed tissue planes, required two surgeries, as well as prolonged antibiotics for complete resolution. Rothia aeria is a rare pathogen that can be added to the spectrum of agents causing disease in CGD, a finding that further reinforces the importance of microbiologic identification of infections in this patient population.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Kuhns DB, Alvord WG, Heller T, Feld JJ, Pike KM, Marciano BE, et al. Residual NADPH oxidase and survival in chronic granulomatous disease. N Engl J Med. 2010;363:2600–10.

    Article  PubMed  CAS  Google Scholar 

  2. Towbin AJ, Chaves I. Chronic granulomatous disease. Pediatr Radiol. 2010;40:657–68. quiz 792-653.

    Article  PubMed  Google Scholar 

  3. Greenberg DE, Shoffner AR, Zelazny AM, Fenster ME, Zarember KA, Stock F, et al. Recurrent Granulibacter bethesdensis infections and chronic granulomatous disease. Emerg Infect Dis. 2010;16:1341–8.

    Article  PubMed  CAS  Google Scholar 

  4. Sugui JA, Vinh DC, Nardone G, Shea YR, Chang YC, Zelazny AM, et al. Neosartorya udagawae (Aspergillus udagawae), an emerging agent of aspergillosis: how different is it from Aspergillus fumigatus? J Clin Microbiol. 2010;48:220–8.

    Article  PubMed  CAS  Google Scholar 

  5. Falcone EL, Hanses S, Stock F, Holland SM, Zelazny AM, Uzel G. Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature. J Clin Immunol 2012.

  6. Li Y, Kawamura Y, Fujiwara N, Naka T, Liu H, Huang X, et al. Rothia aeria sp. nov., Rhodococcus baikonurensis sp. nov. and Arthrobacter russicus sp. nov., isolated from air in the Russian space laboratory Mir. Int J Syst Evol Microbiol. 2004;54:827–35.

    Article  PubMed  CAS  Google Scholar 

  7. Boudewijns M, Magerman K, Verhaegen J, Debrock G, Peetermans WE, Donkersloot P, et al. Rothia dentocariosa, endocarditis and mycotic aneurysms: case report and review of the literature. Clin Microbiol Infection: Off Publ Eur Soc Clin Microbiol Infectious Dis. 2003;9:222–9.

    Article  CAS  Google Scholar 

  8. Salamon SA, Prag J. Three cases of Rothia dentocariosa bacteraemia: frequency in Denmark and a review. Scand J Infect Dis. 2002;34:153–7.

    Article  PubMed  Google Scholar 

  9. Ergin C, Sezer MT, Agalar C, Katirci S, Demirdal T, Yayli G. A case of peritonitis due to Rothia dentocariosa in a CAPD patient. Peritoneal Dialysis Int: J Int Soc Peritoneal Dialysis. 2000;20:242–3.

    CAS  Google Scholar 

  10. Bousquet A, Soler C, Martinaud C, Join-Lambert O, Malfuson JV. Pneumonia and Rothia dentocariosa. Med Mal Infect. 2011;41:621–2.

    Article  PubMed  CAS  Google Scholar 

  11. Favero M, Raffeiner B, Cecchin D, Schiavon F. Septic arthritis caused by Rothia dentocariosa in a patient with rheumatoid arthritis receiving etanercept therapy. J Rheumatol. 2009;36:2846–7.

    Article  PubMed  Google Scholar 

  12. Morley AM, Tuft SJ. Rothia dentocariosa isolated from a corneal ulcer. Cornea. 2006;25:1128–9.

    Article  PubMed  Google Scholar 

  13. MacKinnon MM, Amezaga MR, MacKinnon JR. A case of Rothia dentocariosa endophthalmitis. Eur J Clin Microb Infectious Dis: Off Publ Eur Soc Clin Microbiol. 2001;20:756–7.

    CAS  Google Scholar 

  14. Morgan EA, Henrich TJ, Jarell AD, Shieh WJ, Zaki SR, Marty FM, et al. Infectious granulomatous dermatitis associated with Rothia mucilaginosa bacteremia: A case report. Am J Dermatopathol. 2010;32:175–9.

    Article  PubMed  Google Scholar 

  15. Hodzic E, Snyder S. A case of peritonitis due to Rothia mucilaginosa. Peritoneal Dialysis Int: J Int Soc Peritoneal Dialysis. 2010;30:379–80.

    Article  CAS  Google Scholar 

  16. Lee AB, Harker-Murray P, Ferrieri P, Schleiss MR, Tolar J. Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation. Pediatric Blood Cancer. 2008;50:673–6.

    Article  PubMed  Google Scholar 

  17. Fusconi M, Conti C, De Virgilio A, de Vincentiis M. Paucisymptomatic pneumonia due to Rothia mucilaginosa: case report and literature review. Le Infezioni Med: Riv Period di Eziol, Epidemiol, Diagnostica, Clin Terapia Patologie Infettive. 2009;17:100–4.

    Google Scholar 

  18. Kaasch AJ, Saxler G, Seifert H. Septic arthritis due to Rothia mucilaginosa. Infection. 2011;39:81–2.

    Article  PubMed  CAS  Google Scholar 

  19. Verrall AJ, Robinson PC, Tan CE, Mackie WG, Blackmore TK. Rothia aeria as a cause of sepsis in a native joint. J Clin Microbiol. 2010;48:2648–50.

    Article  PubMed  Google Scholar 

  20. Michon J, Jeulin D, Lang JM, Cattoir V. Rothia aeria acute bronchitis: the first reported case. Infection. 2010;38:335–7.

    Article  PubMed  CAS  Google Scholar 

  21. Hiyamuta H, Tsuruta N, Matsuyama T, Satake M, Ohkusu K, Higuchi K. [First case report of respiratory infection with Rothia aeria]. Nihon Kokyuki Gakkai Zasshi = J Jpn Respir Soc. 2010;48:219–23.

    Google Scholar 

  22. Monju A, Shimizu N, Yamamoto M, Oda K, Kawamoto Y, Ohkusu K. First case report of sepsis due to Rothia aeria in a neonate. J Clin Microbiol. 2009;47:1605–6.

    Article  PubMed  Google Scholar 

Download references

Funding

This work was supported by the Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892. The views expressed in this article are those of the authors and do not reflect the official policy of the U.S. Government.

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to E. Liana Falcone or Steven M. Holland.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Falcone, E.L., Zelazny, A.M. & Holland, S.M. Rothia aeria Neck Abscess in A Patient with Chronic Granulomatous Disease: Case Report and Brief Review of the Literature. J Clin Immunol 32, 1400–1403 (2012). https://doi.org/10.1007/s10875-012-9726-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10875-012-9726-8

Keywords

Navigation