Abstract
In recent years researchers have paid particularly close attention to factors that might differentially influence smoking cessation outcomes in men and women. The present paper reviews empirical findings on gender differences in smoking cessation with focus on 1) nicotine replacement therapy (NRT), 2) depression and anxiety factors, 3) post-cessation weight gain and body-shape concerns, 4) post-cessation withdrawal, and 5) the importance of social support during smoking cessation. The findings call for research to examine the effects of 1) booster sessions following the discontinuation of NRT, 2) depression-prevention interventions for smokers with a history of depression, 3) strategies to prevent weight gain and reduce concerns about weight gain, 4) initiating treatment early in the follicular phase of the menstrual cycle, and 5) social support variables in promoting or hindering smoking cessation success.
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Allen, S. S., Hatsukami, D., Christianson, D., & Brown, S. (2000). Effects of transdermalnicotine on craving, withdrawal and premenstrual symptomatology in short-term smoking abstinence during phases of the menstrual cycle. Nicotine and Tobacco Research, 2, 231–241.
American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
Benowitz, N. L. (Ed.). (1998). Nicotine safety and toxicity. New York: Oxford University Press.
Bjornson, W., Rand, C., Connett, J. E., Lindgren, P., Nides, M., Pope, F., Buist, A. S., Hoppe-Ryan, C., & O’Hara, P. (1995). Gender differences in smoking cessation after 3 years in the Lung Health Study. American Journal of Public Health, 85, 223–230.
Blazer, D., Kessler, R., McGonagle, K., & Swartz, S. (1994). The prevalence and distribution of major depression in a national community sample: The National Comorbidity Survey. American Journal of Psychiatry, 151, 979–986.
Bock, B. C., Goldstein, M. G., & Marcus, B. H. (1996). Depression following smoking cessation in women. Journal of Substance Abuse, 8, 137–144.
Borlan, R. (1990). Slip-ups and relapse in attempts to quit smoking. Addictive Behaviors, 15, 235–245.
Breslau, N., Kilbey, M. M., & Andreski, P. (1992). Nicotine withdrawal symptoms and psychiatric disorders: Findings from an epidemiological study of young adults. American Journal of Psychiatry, 149, 464–469.
Breslau, N., Kilbey, M. M., & Andreski, P. (1993). Nicotine dependence and major depression: New evidence from a prospective investigation. Archives of General Psychiatry, 50, 31–35.
Burton, S. L., Gitcell, J. G., & Shiffman, S. (2000). Use of FDA-approved pharmacological treatments for tobacco dependence: United States 1984–1998. Morbidity and Mortality Weekly Report, 49, 665-668.
Cameron, I. T., Fraser, I. S., & Smith, S. K. (1998). Clinical disorders of the endometrium and menstrual cycle. Oxford: Oxford University Press.
Cepeda-Benito, A. (1993). Meta-analytical review of the efficacy of nicotine chewing gum in smoking treatment programs. Journal of Consulting and Clinical Psychology, 61, 822–830.
Cepeda-Benito, A., & Reig-Ferrer, A. (2000). Smoking consequences questionnaire—Spanish. Psychology of Addictive Behaviors, 14, 219–230.
Cepeda-Benito, A., Reynoso, J., & Erath, S. (2004). Meta-analysis of the efficacy of nicotine replacement therapy for smoking cessation: Differences between men and women. Journal of Consulting and Clinical Psychology, 72, 712–722.
Cepeda-Benito, A., Reynoso, J., & Susabda, A. (2004). Review of the effectiveness of nicotine replacement therapy for smoking cessation in men and women. Revista Internacional de Psicología, 1, 91-117.
Covey, L. S., Glassman, A. H., Stetner, F., & Becker, J. (1993). Effect of history of alcoholism or major depression on smoking cessation. American Journal of Psychiatry, 150, 1546–1547.
Craig, D., Parrott, A., & Coomber, J. (1992). Smoking cessation in women: Effects of the menstrual cycle. International Journal of the Addiction, 27, 697–707.
Fiore, M. C., Bailey, W. C., Cohen, S. J., Dorfman, S. F., Fox, B. J., Goldstein, M. G., et al. (2000). A clinical practice guideline for treating tobacco use and dependence —A US Public Health Service report. JAMA, 283, 3244–3254.
Froom, P., Melamed, S., & Benbassat, J. (1998). Smoking cessation and weight gain. Journal of Family Practice, 46, 460–464.
Fujita, F., Deiner, E., & Sandvik, E. (1991). Gender differences in negative affect and well-being: The case for emotional intensity. Journal of Personality and Social Psychology, 61, 427–434.
Glasgow, R. E., Strycker, L. A., Eakin, E. G., Boles, S. M., & Whitlock, E. P. (1999). Concern about weight gain associated with quitting smoking: Prevalence and association with outcome in a sample of young female smokers. Journal of Consulting and Clinical Psychology, 67, 1009–1011.
Glassman, A. H., Covey, L. S., Dalack, G. W., Stetner, F., Rivelli, S., & Fliess, J. (1993). Smoking cessation, clonidinde, and vulnerability to nicotine among dependent smokers. Clinical Pharmacology and Therapeutics, 54, 670–679.
Gourlay, S. G., Forbes, A., Marriner, T., Pethica, D., & McNeil, J. J. (1994). Prospective study of factors predicting outcome of transdermal nicotine treatment in smoking cessation. BMJ, 305, 842–846.
Gritz, E. R., Nielsen, I. R., & Brooks, L. A. (1996). Smoking cessation and gender: The influence of physiological, psychological, and behavioral factors. Journal of the American Medical Women’s Association, 51(1–2), 35–42.
Gunn, R. C. (1986). Reactions to withdrawal symptoms and success in smoking cessation clinics. Addictive Behaviors, 11, 49-53.
Hajek, P., West, R., Foulds, J., Nilsson, F., Burrows, S., & Meadow, A. (1999). Randomized comparative trial of nicotine polacrilex, a transdermal patch, nasal spray, and an inhaler. Archives of Internal Medicine, 159, 2033–2038.
Hanson, B. S., Isacsson, S. O., Janzon, L., & Lindell, S. E. (1990). Social support and quitting smoking for good is there an association? Results from the population study, “Men born in 1914”, Malmo, Sweden. Addictive Behaviors, 15, 221–233.
Hatsukami, D., Skoog, K., Allen, S., & Bliss, R. (1995). Gender and the effects of different doses of nicotine gum on tobacco withdrawal symptoms. Experimental and Clinical Psychopharmacology, 3, 163–173.
Henningfield, J. E. (1995). Drug therapy: Nicotine medications for smoking cessation. New England Journal of Medicine, 333, 1196–1203.
Henningfield, J. E., London, E. D., & Jaffe, J. H. (1987). Nicotine reward: Studies of the abuse liability and physical dependence potential. In J. Engel & L. Oreland (Eds.), Brain Reward Systems and Abuse (pp. 147–164). New York: Raven.
Hill, A. L., Roe, D. J., Taren, D. L., Muramoto, M. M., & Leischow, S. J. (2000). Efficacy of transdermal nicotine in reducing post-cessation weight gain in a Hispanic sample. Nicotine and Tobacco Research, 2, 247–253.
Hitsman, B., Borrelli, B., McChargue, D. E., Spring, B., & Niaura, R. (2003). History of depression and smoking cessation outcome: A meta-analysis. Journal of Consulting and Clinical Psychology, 71, 657–663.
Hughes, J. R., Higgins, S. T., & Hatsukami, D. (1990). Effects of abstinence from tobacco: A critical review. In L. T. Kozlowski, H. M. Annis, H. D. Cappell, F. Glasser, M. Goodstadt, Y. Israel, H. Kalant, E. M. Sellers, & J. Vingillis (Eds.), Research advances in alcohol and drug problems (Vol. 10, pp. 317–398). New York: Plenum.
Jorenby, D. E., Leischow, S. J., Nides, M. A., Rennard, S. I., Johnston, J. A., Hughes, A. R., et al. (1999). A controlled trial of sustained-release bupropion, a nicotine patch, or both for smoking cessation. New England Journal of Medicine, 340, 685–691.
Kawachi, I., Troisi, R. J., Rotnizky, A. G., & Coakley, E. H. (1996). Can physical activity minimize weight gain in women after smoking cessation? American Journal of Public Health, 86, 999-1004.
Kendler, K. S., Neale, M. C., MacLean, C. J., Heath, A. C., Eaves, L. J., & Kessler, R. C. (1993). Smoking and major depression: A casual analysis. Archives of General Psychiatry, 50, 36–43.
Killen, J. D., Fortmann, S. P., Schatzberg, A. F., Hayward, C., Sussman, L., Rothman, M., et al. (2000). Nicotine replacement therapy and paroxetine for smoking cessation. Journal of Consulting and Clinical Psychology, 68, 883–889.
Killen, J. D., Fortmann, S. P., Schatzberg, A., Hayward, C., & Varady, A. (2003). Onset of major depression during treatment for nicotine dependence. Addictive Behaviors, 28, 461–470.
Klesges, R. C., Winders, S. E., Meyers, A. W., Eck, L. H., Ward, K. D., Hulquist, C. M., et al. (1997). How much weight gain occurs following smoking cessation? A comparison of weight gain using both continuous and point prevalence abstinence. Journal of Consulting and Clinical Psychology, 65, 286–291.
Marcus, B. H., Albrecht, A. E., King, T. K., Parisi, A. F., Pinto, B. M., Roberts, M., et al. (1999). The efficacy of exercise as an aid to smoking cessation in women. Archives of Internal Medicine, 159, 1229–1234.
McKee, S. A., Maciejewski, P. K., Falba, T., & Mazure, C. M. (2003). Sex differences in the effects of stressful life events on changes in smoking status. Addiction, 98, 847–855.
Murray, R. P., Johnston, J. J., Dolce, J. J., Lee, W. W., & O’Hara, P. (1995). Social support for smoking cessation and abstinence: The Lung Health Study. Addictive Behaviors, 20, 159–170.
Niaura, R., Britt, D. M., Borrelli, B., Shadel, W. G., Abrams, D. B., & Goldstein, M. G. (1999). Nicotine and Tobacco Research, 1, 251–258.
Ogden, J., & Fox, P. (1994). Examination of the use of smoking for weight control in restrained and unrestrained eaters. International Journal of Eating Disorders, 16, 177–185.
Perkins, K. A. (1994). Issues in the prevention of weight gain after smoking cessation. Annuals of Behavioral Medicine, 16, 46–52.
Perkins, K. A. (1996). Sex differences in nicotine versus non-nicotine reinforcement as determinants of tobacco smoking. Experimental and Clinical Psychopharmacology, 4, 166–177.
Perkins, K. A. (2001). Smoking cessation in women: Special considerations. CNS Drugs, 15, 391–411.
Perkins, K. A., Donny, E., & Caggiula, A. R. (1999). Sex differences in nicotine effects and self-administration: Human and animal evidence. Nicotine and Tobacco Research, 1, 301–315.
Perkins, K. A., Levine, M., Marcus, M., Shiffman, S., D’Amico, D., Miller, A., et al. (2000). Tobacco withdrawal in women and the menstrual cycle phase. Journal of Consulting and Clinical Psychology, 68, 176–180.
Piasecki, T. M., Niaura, R., Shadel, W. G., Abrams, D., Goldstein, M., Fiore, M. C., et al. (2000). Smoking withdrawal dynamics in unaided quitters. Journal of Abnormal Psychology, 109, 74–86.
Pomerleau, C. S., Marks, J. L., & Pomerleau, O. F. (2000). Who gets what symptom? Effect of psychiatric cofactors and nicotine dependence on patterns of smoking withdrawal symptomatology. Nicotine and Tobacco Research, 2, 275–280.
Pomerleau, C. S., Tate, J. C., Lumley, M. A., & Pomerleau, O. F. (1994). Gender differences in prospectively versus retrospectively assessed smoking withdrawal symptoms. Journal of Substance Abuse, 6, 433–440.
Pomerleau, C. S., Zucker, A. N., & Stewart, A. J. (2003). Patterns of depressive symptomatology in women smokers, ex-smokers, and never-smokers. Addictive Behaviors, 28, 575–582.
Rigotti, N. A., Thorndike, A. N., & Duncan, M. J. (2000). Post-cessation weight gain in smokers taking bupropion: The effect of gender [abstract]. In Proceedings of the 6th Annual Meeting of the Society for Research on Nicotine and Tobacco, February 18–20, Arlington, VA.
Schwartz, R., & Leppin, A. (1989). Social support and health: A meta-analysis. Psychological Health, 3, 1–15.
Stockton, M. C., McMahon, S. D., & Jason, L. A. (2000). Gender and smoking behavior in a worksite smoking cessation program. Addictive Behaviors, 25, 347–360.
Tate, J. C., Pomerleau, O. F., & Pomerleau, C. S. (1993). Temporal stability and within-subject consistency of nicotine withdrawal symptoms. Journal of Substance Abuse, 5, 355–363.
U. S. Department of Health, Education, and Welfare (1964). Smoking and Health Report of the Advisory Committee to the Surgeon General of the Public Health Service. Rockville, MD: U. S. Department of Health, Education, and Welfare, Public Health Service, Office of the surgeon General.
U. S. Department of Health and Human Services. (1980). The health consequences of smoking for women. A report of the Surgeon General. Washington, DC: U. S. Department of Health and Human Services, Public Health Service, Office of the Assistant Secretary for Health, Office on Smoking and Health, 1980.
U. S. Department of Health and Human Services. (1988). The health consequences of smoking: Nicotine addiction. A report of the Surgeon General. Atlanta, GA: U. S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, Center for Health Promotion and Education, Office of the Assistant Secretary for Health, Office on Smoking and Health, 1988. DHHS Publication No. (CDC) 88–8406.
U. S. Department of Health and Human Services. (2001). Women and smoking: A report of the Surgeon General. Rockville, MD: U. S. Department of Health and Human Services, Public Health Service, Office of the Surgeon General.
Wetter, D. W., Anderson, C. B., DeMoore, C. A., Cinciripini, P. M., Carmack, C. L., Moore, C. A., et al. (2000). Tobacco withdrawal signs and symptoms among women with and without a history of depression. Experimental and Clinical Psychopharmacology, 8, 88–96.