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Elective transfer of two embryos: Reduction of multiple gestations while maintaining high pregnancy rates

  • Assisted Reproduction
  • Published:
Journal of Assisted Reproduction and Genetics Aims and scope Submit manuscript

Abstract

Purpose: To determine if the elective transfer of two embryos reduced the incidence of multiple gestations while maintaining high pregnancy rates. Methods: IVF patients and recipients of oocyte donation with an elective day-3 transfer of 2 or 3 embryos were studied. Result(s): In IVF, the elective transfer of 2 embryos resulted in similar pregnancy rate but significantly reduced the overall incidence of multiple gestations (20% versus 39%) when compared to the elective transfer of 3 embryos. Twin gestations decreased from 28% to 19%, and triplets significantly decreased from 9% to 1%. In oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rate but also significantly reduced the overall incidence of multiple gestations (26% versus 48%), with twins decreasing from 34% to 24%, and with a significant reduction of triplets (13% versus 2%). Conclusions: In IVF and oocyte donation, the elective transfer of 2 embryos resulted in similar pregnancy rates and significantly reduced multiple gestation rates when compared to the elective transfer of 3 embryos.

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Authors and Affiliations

  1. The Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, 601 Colley Avenue, Norfolk, Virginia, 23507, USA

    Donna Dowling-Lacey, Estella Jones, Jacob Mayer, Silvina Bocca, Laurel Stadtmauer & Sergio Oehninger

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  1. Donna Dowling-Lacey
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  2. Estella Jones
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  3. Jacob Mayer
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  4. Silvina Bocca
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  5. Laurel Stadtmauer
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  6. Sergio Oehninger
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Correspondence to Sergio Oehninger.

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Dowling-Lacey, D., Jones, E., Mayer, J. et al. Elective transfer of two embryos: Reduction of multiple gestations while maintaining high pregnancy rates. J Assist Reprod Genet 24, 11–15 (2007). https://doi.org/10.1007/s10815-006-9085-6

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  • DOI: https://doi.org/10.1007/s10815-006-9085-6

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