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Assessing surrogacy of data sources for institutional comparisons

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Abstract

Can administrative claims data, Z, serve as a surrogate for better clinical data, X, when assessing institutional performance? We consider an analysis of I hospitals, each of which involves an adjusted outcome. In the i th hospital, we denote the true association between the outcome and the risk factors using one data source by θ i (X), the true association between the outcome and the risk factors using the other data source by γ i (Z), and assume we have estimates of each available. Within hospital i, the estimated association parameters are jointly normally distributed such that conditional on γ i (Z), a simple linear relationship exists between θ i (X) and γ i (Z). Methods are illustrated using mortality rates for 181,032 elderly US heart attack patients treated at 4322 hospitals. We find a strong linear relationship between the hospital standardized mortality rates adjusted by risk factors found in administrative claims data and rates adjusted by risk factors found in medical charts (posterior mean [95% interval] for slope: 0.997 [0.965,1.028]). However, the absolute and relative differences between the two sets of rates increase as hospital volume increases. For typically-sized standard deviations of claims-based rates, there is reasonable certainty of quality problems when the hospital’s claims-based rate is 0.72 times or smaller than the national mean or 1.45 times or greater than the national mean. Fewer hospitals are classified as either low-mortality or high-mortality hospitals when using claims-based estimates compared to chart-based estimates.

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Acknowledgements

The authors thank Jennifer Mattera, Amy Rich, Yongfei Wang, Deron Galusha, Inyoung Kim; and the clinical experts (Jeptha Curtis, Robert McNamara, Mikhail Kosiborod). The analyses upon which this publication is based were performed under Contract Number 500-02-C001, entitled “Utilization and Quality Control Quality Improvement Organization for the State (commonwealth) of Colorado”, sponsored by the Centers for Medicare & Medicaid Services (formerly Health Care Financing Administration), Department of Health and Human Services. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commercial products, or organizations imply endorsement by the US government. The authors assume full responsibility for the accuracy and completeness of the ideas presented. Dr. Normand’s effort was partially supported by Grant MH54693 from the National Institute of Mental Health.

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Correspondence to Sharon-Lise T. Normand.

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Normand, SL.T., Wang, Y. & Krumholz, H.M. Assessing surrogacy of data sources for institutional comparisons. Health Serv Outcomes Res Method 7, 79–96 (2007). https://doi.org/10.1007/s10742-006-0018-8

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  • DOI: https://doi.org/10.1007/s10742-006-0018-8

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