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Differences between women and men in serial HIV prevalence and incidence trends

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Abstract

To measure trends in HIV incidence and serial prevalence by sex in a intravenous drug users (IDUs) and heterosexuals (HT) cohort recruited in a counselling centre in Valencia (1988–2005). Serial prevalence and incidence rates were calculated and modelled by logistic and Poisson regression respectively. 5948 IDUs and 13343 HT were recruited. Prevalence was higher among female IDUs (46% vs. 41%), and female HT (4.1% vs. 2%). For IDUs, an interaction (P = 0.005) between sex and calendar was detected. Age-adjusted prevalence showed faster yearly decline in men (OR = 0.87 95%CI: 0.85–0.88) than in women (OR = 0.91 95%CI: 0.88–0.93). Incidence was higher in female IDUs (9.79% p-y) than in men, (5.38% p-y) with an annual decrease for both of 11%. HIV incidence was higher in female HT (0.62% p-y) compared to men 0.23% p-y with a 21% yearly decline. Gender differences in HIV prevalence and incidence trends have been detected. Women showed an increased vulnerability to infection in a country whose HIV epidemic has been largely driven by IDUs.

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Abbreviations

CIPS:

Centre for AIDS Information and Prevention

HT:

Heterosexuals

HAV:

Hepatitis A virus

HBV:

Hepatitis B virus

HCV:

Hepatitis C virus

IDU:

Intravenous drug users

RR:

Rates ratio

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Acknowledgements

Sponsorship: This work was financed through grants from Fondo de Investigación Sanitaria (FIS) (02/0639) and Becas de la Consellería de Sanitat de la Generalitat Valenciana B12/03 y B15/04.

Authorship: I. Hurtado, designed the study, I Hurtado and S Pérez-Hoyos carried out the statistical analysis. I. Alastrue, C. Santos and T. Tasa were responsible for the recruitment and data collection. S. Pérez-Hoyos set up the original study and collaborated in its design. I. Hurtado, S. Pérez-Hoyos and J. Del Amo wrote and interpreted the results. All the authors revised the different versions of the manuscript.

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Authors and Affiliations

  1. Ciber en Epidemiología y Salud Pública (CIBERESP), Barcelona, Spain

    Isabel Hurtado Navarro, I. Ferreros & S. Pérez-Hoyos

  2. Unitat d’Epidemiologia i Estadística, Escola Valenciana d’Estudis en Salut (EVES), C/ Juan de Garay 21, 46017, Valencia, Spain

    Isabel Hurtado Navarro, I. Ferreros & S. Pérez-Hoyos

  3. Centro de Información y Prevención del SIDA de Valencia, Valencia, Spain

    I. Alastrue, C. Santos & T. Tasa

  4. Dpto. Salud Pública, Universidad Miguel Hernández de Alicante, Alicante, Spain

    J. del Amo

  5. Dpto. Enfermería Comunitaria, Medicina Preventiva y Salud Pública e Historia de la Ciencia, Universidad de Alicante, Alicante, Spain

    S. Pérez-Hoyos

Authors
  1. Isabel Hurtado Navarro
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  2. I. Alastrue
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  3. J. del Amo
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  4. C. Santos
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  5. I. Ferreros
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  6. T. Tasa
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  7. S. Pérez-Hoyos
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Correspondence to Isabel Hurtado Navarro.

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Hurtado Navarro, I., Alastrue, I., del Amo, J. et al. Differences between women and men in serial HIV prevalence and incidence trends. Eur J Epidemiol 23, 435–440 (2008). https://doi.org/10.1007/s10654-008-9246-2

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  • DOI: https://doi.org/10.1007/s10654-008-9246-2

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