Chromatographic separation of the 80% aqueous methanol extract (AME) of Jatropha multifida Linn. leaves has yielded three novel biapigenin di-C-glucosides, i.e., 6,6″-di-C-β-glucopyranosyl-methylene-(8,8″)biapigenin (7), 3,6″-di-C-β-glucopyranosyl-methylene-(6,8″)-biapigenin (8), and 6,6″-di-C-β-glucopyranosyl-methylene-(3,8″)-biapigenin (9), named jatrophenols I–III. In addition, seven known polyphenolic metabolites were identified as apigenin 7-O-β-neohespredoside (1), ferulic acid (2), quercetrin (3), vicinin-II (4), isoorientin (5), vitexin (6), and luteolin (10) for the first time from this species. The AME of the plant was reported for the first time to have significant analgesic, anti-inflammatory, and antihypertensive effects.
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Published in Khimiya Prirodnykh Soedinenii, No. 5, September–October, 2012, pp. 685–689.
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Marzouk, M.S., Moharram, F.A., Haggag, E.G. et al. Novel biflavone diglycosides and biological activity of Jatropha multifida leaves. Chem Nat Compd 48, 765–770 (2012). https://doi.org/10.1007/s10600-012-0377-z
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DOI: https://doi.org/10.1007/s10600-012-0377-z