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Food groups and risk of prostate cancer: a case–control study in Uruguay

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Abstract

Objective

The role of foods and beverages has been studied in detail in order to establish probable risk factors for prostate cancer.

Methods

Data were derived from 326 cases with incident and microscopically confirmed adenocarcinomas of the prostate and 652 controls. Odds ratios and 95 % confidence intervals of prostate cancer were estimated by unconditional multiple logistic regression.

Results

We identified the following food items as risk factors: lamb meat, salted meat, whole milk, total eggs, and maté consumption. The highest OR was associated with total eggs (OR, 2.43; 95 % CI, 1.70–3.48), followed by salted meat (OR, 2.65; 95 % CI, 1.36–3.76), maté consumption (OR, 1.96; 95 % CI, 1.17–3.31), and whole milk (OR, 2.01; 95 % CI, 1.26–2.51).

Conclusions

The final model, fitted by stepwise forward method, included total eggs, salted meat, whole milk, and maté consumption, whereas fruits were protective.

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Acknowledgments

This study was funded by the International Agency for Research on Cancer, Lyon, France.

Conflicts of interests

None.

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Authors and Affiliations

  1. Grupo de Epidemiología, Departamento de Anatomía Patológica, Hospital de Clínicas, Universidad de la República, Avenida Brasil 3080 department 402, 11300, Montevideo, Uruguay

    Hugo Deneo-Pellegrini, Eduardo De Stefani, María Mendilaharsu & Gisele Acosta

  2. Departamento de Epidemiología, IUCLAEH Universidad de Maldonado, Maldonado, Uruguay

    Alvaro L. Ronco

  3. The Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY, USA

    Paolo Boffetta

  4. Division of Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center, Nashville, TN, USA

    Pelayo Correa

Authors
  1. Hugo Deneo-Pellegrini
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  2. Alvaro L. Ronco
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  3. Eduardo De Stefani
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Correspondence to Eduardo De Stefani.

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Deneo-Pellegrini, H., Ronco, A.L., De Stefani, E. et al. Food groups and risk of prostate cancer: a case–control study in Uruguay. Cancer Causes Control 23, 1031–1038 (2012). https://doi.org/10.1007/s10552-012-9968-z

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  • DOI: https://doi.org/10.1007/s10552-012-9968-z

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