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Group Motivational Interviewing to Promote Adherence to Antiretroviral Medications and Risk Reduction Behaviors in HIV Infected Women

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Abstract

We present the results of a clinical trial that tested the efficacy of using motivational interviewing (MI) in a group format to promote adherence to antiretroviral medications and risk reduction behaviors (RRB) in 203 predominately African American HIV infected women. It was compared to a group health promotion program. Participants were followed for 9 months. Adherence was measured by MEMS®; and RRB by self-report. Controlling for recruitment site and years on ART, no significant group by time effects were observed. Attendance (≥7/8 sessions) modified the effects. Higher MI attendees had better adherence at all follow-ups, a borderline significant group by time effect (p = 0.1) for % Doses Taken on Schedule, a significantly larger proportion who reported abstinence at 2 weeks, 6, and 9 months, and always used protection during sex at 6 and 9 months. Though not conclusive, the findings offer some support for using MI in a group format to promote adherence and some risk reduction behaviors when adequate attendance is maintained.

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References

  1. CDC. Effect of antiretroviral therapy on risk of sexual transmission of HIV infection and superinfection: centers for disease control and prevention. 2009 September.

  2. CDC. Recommendations for use of antiretroviral drugs in pregnant HIV-infected women for maternal health and interventions to reduce perinatal HIV transmission in the United States. 2009 [cited 2009 October 18].

  3. Remien RH, Exner T, Kertzner RM, Ehrhardt AA, Rotheram-Borus MJ, Johnson MO, et al. Depressive symptomatology among HIV-positive women in the era of HAART: a stress and coping model. Am J Community Psychol. 2006;38(3–4):275–85.

    Article  PubMed  Google Scholar 

  4. Wilson TE, Barron Y, Cohen M, Richardson J, Greenblatt R, Sacks HS, et al. Adherence to antiretroviral therapy and its association with sexual behavior in a national sample of women with human immunodeficiency virus. Clin Infect Dis. 2002;34(4):529–34.

    Article  PubMed  Google Scholar 

  5. Kalichman S, Rompa D. HIV treatment adherence and unprotected sex practices in people receiving antiretroviral therapy. Sex Transm Infect. 2003;79:59–61.

    Article  PubMed  CAS  Google Scholar 

  6. Diamond C, Richardson JL, Milam J, Stoyanoff S, McCutchan JA, Kemper C, et al. Use of and adherence to antiretroviral therapy is associated with decreased sexual risk behavior in HIV clinic patients. J AIDS. 2005;39(2):211–8.

    Google Scholar 

  7. Remien RH, Exner TM, Morin SF, Ehrhardt AA, Johnson MO, Correale J, et al. Medication adherence and sexual risk behavior among HIV-infected adults: implications for transmission of resistant virus. AIDS Behav. 2007;11(5):663–75.

    Article  PubMed  Google Scholar 

  8. Donnell D, Baeten jM, Kiarie j, Thomas KK, Stevens W, Cohen CR, McIntyre J, Lingappa JR, Celum C. Heterosexual HIV-1 transmission after initiation of antiretroviral therapy: a prospective cohort analysis. Lancet. 2010;375:2092–8.

    Article  PubMed  Google Scholar 

  9. Bennett JA, Young HM, Nail LM, Winters-Stone K, Hanson G. A telephone-only motivational intervention to increase physical activity in rural adults: a randomized controlled trial. Nurs Res. 2008;57(1):24–32.

    Article  PubMed  Google Scholar 

  10. Resnicow K, Wallace DC, Jackson A, Digirolamo A, Odom E, Wang T, et al. Dietary change through African American churches: baseline results and program description of the eat for life trial. J Cancer Educ. 2000;15(3):156–63.

    Google Scholar 

  11. Smith DE, Heckemeyer CM, Kratt PP, Mason DA. Motivational interviewing to improve adherence to a behavioral weight-control program for older obese women with NIDDM. A pilot study. Diabetes Care. 1997;20(1):52–4.

    Article  PubMed  CAS  Google Scholar 

  12. Stein MD, Herman DS, Anderson BJ. A motivational intervention trial to reduce cocaine use. J Subst Abuse Treat. 2009;36(1):118–25.

    Article  PubMed  Google Scholar 

  13. Parsons JT, Golub SA, Rosof E, Holder C. Motivational interviewing and cognitive-behavioral intervention to improve HIV medication adherence among hazardous drinkers: a randomized controlled trial. J AIDS. 2007;46(4):443–50.

    Google Scholar 

  14. Velasquez MM, von Sternberg K, Johnson DH, Green C, Carbonari JP, Parsons JT. Reducing sexual risk behaviors and alcohol use among HIV-positive men who have sex with men: a randomized clinical trial. J Consult Clin Psychol. 2009;77(4):657–67.

    Article  PubMed  Google Scholar 

  15. DiIorio C, McCarty F, Resnicow K, McDonnell Holstad M, Soet J, Yeager K, et al. Using motivational interviewing to promote adherence to antiretroviral medications: a randomized controlled study. AIDS Care. 2008;20(3):273–83.

    Article  PubMed  CAS  Google Scholar 

  16. Golin CE, Earp J, Tien HC, Stewart P, Porter C, Howie L. A 2-arm, randomized, controlled trial of a motivational interviewing-based intervention to improve adherence to antiretroviral therapy (ART) among patients failing or initiating ART. J AIDS. 2006;42(1):42–51.

    Google Scholar 

  17. Fisher JD, Fisher WA, Cornman DH, Amico RK, Bryan A, Friedland GH. Clinician-delivered intervention during routine clinical care reduces unprotected sexual behavior among HIV-infected patients. J AIDS. 2006;41(1):44–52.

    Google Scholar 

  18. Callahan EJ, Flynn NM, Kuenneth CA, Enders SR. Strategies to reduce HIV risk behavior in HIV primary care clinics: brief provider messages and specialist intervention. AIDS Behav. 2007;11(5 Suppl):S48–57.

    Article  PubMed  Google Scholar 

  19. Golin CE, Patel S, Tiller K, Quinlivan EB, Grodensky CA, Boland M. Start talking about risks: development of a motivational interviewing-based safer sex program for people living with HIV. AIDS Behav. 2007;11(5 Suppl):S72–83.

    Article  PubMed  Google Scholar 

  20. Nollen C, Drainoni ML, Sharp V. Designing and delivering a prevention project within an HIV treatment setting: lessons learned from a specialist model. AIDS Behav. 2007;11(5 Suppl):S84–94.

    Article  PubMed  Google Scholar 

  21. Rutledge SE. Single-session motivational enhancement counseling to support change toward reduction of HIV transmission by HIV positive persons. Arch Sex Behav. 2007;36(2):313–9.

    Article  PubMed  Google Scholar 

  22. Ingersoll K, Wagner C. Motivational enhancement groups for the Virginia substance abuse treatment outcome evaluation (SATOE) model: theoretical background and clinical guidelines. Richmond, VA: Virginia Addiction Technology Transfer Center Virginia Commonwealth University/Medical College of Virginia; 1998.

    Google Scholar 

  23. Morrison-Beedy D, Carey MP, Kowalski J, Tu X. Group-based HIV risk reduction intervention for adolescent girls: evidence of feasibility and efficacy. Res Nurs Health. 2005;28(1):3–15.

    Article  PubMed  Google Scholar 

  24. Holstad MM, DiIorio C, Magowe MK. Motivating HIV positive women to adhere to antiretroviral therapy and risk reduction behavior: the KHARMA Project. Online J Issues Nurs. 2006;11(1):5.

    PubMed  Google Scholar 

  25. Ebbert DW, Connors H. Standardized patient experiences: evaluation of clinical performance and nurse practitioner student satisfaction. Nurs Educ Perspect. 2004;25(1):12–5.

    PubMed  Google Scholar 

  26. CDC. Revision of the CDC surveillance case definition for acuired immunodeficiency syndrome. MMWR. 1987;36(1S):82–94.

    Google Scholar 

  27. CDC. Core measures for HIV/STD risk behavior and prevention: Questionnaire-based measurement for surveys and other data systems. Sexual behavior questions version 5.00. 2001 [5/27/2003.].

  28. Metzger DS, Koblin B, Turner C, Navaline H, Valenti F, Holte S, et al. Randomized controlled trial of audio computer-assisted self-interviewing: utility and acceptability in longitudinal studies. HIVNET vaccine preparedness study protocol team. Am J Epidemiol. 2000;152(2):99–106.

    Article  PubMed  CAS  Google Scholar 

  29. Williams M, Bowen A, Ross M, Freeman R, Elwood W. Perceived compliance with AZT dosing among a sample of African-American drug users. Int J STD AIDS. 2000;11(1):57–63.

    Article  PubMed  CAS  Google Scholar 

  30. Radloff LS. The CES-D scale: a self-report depression scale for research in the general population. Appl Psychol Meas. 1977;1:385–401.

    Article  Google Scholar 

  31. Paterson DL, Swindells S, Mohr J, Brester M, Vergis EN, Squier C, et al. Adherence to protease inhibitor therapy and outcomes in patients with HIV infection. Ann Intern Med. 2000;133:21–30.

    PubMed  CAS  Google Scholar 

  32. Jones DL, McPherson-Baker S, Lydston D, Camille J, Brondolo E, Tobin JN, et al. Efficacy of a group medication adherence intervention among HIV positive women: the SMART/EST Women’s Project. AIDS Behav. 2007;11(1):79–86.

    Article  PubMed  Google Scholar 

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Acknowledgments

This research was funded by a grant from the National Institutes of Nursing Research R01 NR008094. We wish to thank the women who participated in this project and the providers and staff of the clinics from which we recruited and conducted the study. We also acknowledge the work of the KHARMA Project staff, including Bridget Jones, Carol Corkran, Sally Carpentier, Versey McLendon, Lisa Weaver, Kate Yeager, Samaha Norris, Ilya Teplinskiy, and Frances McCarty.

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Correspondence to Marcia McDonnell Holstad.

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Holstad, M.M., DiIorio, C., Kelley, M.E. et al. Group Motivational Interviewing to Promote Adherence to Antiretroviral Medications and Risk Reduction Behaviors in HIV Infected Women. AIDS Behav 15, 885–896 (2011). https://doi.org/10.1007/s10461-010-9865-y

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  • DOI: https://doi.org/10.1007/s10461-010-9865-y

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