Skip to main content

Advertisement

Log in

The Utility of Non-proportional Quota Sampling for Recruiting At-risk Women for Microbicide Research

  • Original Paper
  • Published:
AIDS and Behavior Aims and scope Submit manuscript

Abstract

In the context of a measurement development study designed to contextualize microbicide acceptability, a sample that represented a range of at-risk women and maintained the statistical power needed for validity analyses was required. A non-proportional quota sampling strategy focused on race/ethnicity and number of sexual partners was utilized. This strategy resulted in enrollment of approximately equal proportions of Latina (31%), Black (36%), and White (32%) women, and an approximately 1:2 ratio of single-partnered (29%) and multi-partnered (71%) women. About 17% of women screened were ineligible based on eligibility criteria; an additional 16% were ineligible based on quota closures. Most participants were recruited through word of mouth (39%), community-based organizations (19%), or media sources (19%). Women recruited through word of mouth had the highest screen-to-interview completion percentage (67%). Non-proportional quota sampling is a feasible option for ensuring adequate representation of sample characteristics in microbicide research, but this goal should be weighed against cost and staff burden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Braunstein, M. S. (1993). Sampling a hidden population: Noninstitutionalized drug users. AIDS Education and Prevention, 5(2), 131–140.

    PubMed  CAS  Google Scholar 

  • Carballo-Diéguez, A., O’Sullivan, L. F., Lin, P., Dolezal, C., Pollack, L., & Catania, J. (2006). Awareness and attitudes regarding microbicides and nonoxynol-9 use in a probability sample of gay men. AIDS and Behavior.

  • Centers for Disease Control and Prevention. (2005). HIV/AIDS Surveillance Report, 2004 (Vol. 16). Atlanta, GA: US Department of Heath and Human Services, CDC.

    Google Scholar 

  • Coggins, C., Elias, C. J., Atisook, R., Bassett, M. T., Ettiegnene-Traore, V., & Ghys, P. D., et al. (1998). Women’s preferences regarding the formulation of over-the-counter vaginal spermicides. AIDS, 12(11), 1389–1391.

    Article  PubMed  CAS  Google Scholar 

  • Cohen J. A., Steele M. S., Urena F. I., & Beksinska, M. E. (2007). Microbicide applicators: Understanding design preferences among women in the Dominican Republic and South Africa. Sexually Transmitted Diseases, 34(1), 15–19.

    Article  PubMed  Google Scholar 

  • Coleman, E. A., Tyll, L., LaCroix, A. Z., Allen, C., Leveille, S. G., & Wallace, J. I., et al. (1997). Recruiting African–American older adults for a community-based health promotion intervention: Which strategies are effective? American Journal of Preventive Medicine, 13(6 Suppl), 51–56.

    PubMed  CAS  Google Scholar 

  • Collins, R. L. (1996). The role of ethnic versus nonethnic sociocultural factors in substance use and misuse. Substance Use and Misuse, 31(1), 95–101.

    PubMed  CAS  Google Scholar 

  • Darroch, J. E., & Frost, J. J. (1999). Women’s interest in vaginal microbicides. Family Planning Perspectives, 31(1), 16–23.

    Article  PubMed  CAS  Google Scholar 

  • Deren, S., Shedlin, M., Decena, C. U., & Mino, M. (2005). Research challenges to the study of HIV/AIDS among migrant and immigrant Hispanic populations in the United States. Journal of Urban Health, 82(2 Suppl 3), iii13–25.

    PubMed  Google Scholar 

  • Dilworth-Anderson, P., & Williams, S. W. (2004). Recruitment and retention strategies for longitudinal African American caregiving research: The Family Caregiving Project. Journal of Aging and Health, 16(5 Suppl), 137S–156S.

    Article  PubMed  Google Scholar 

  • Dunn, C. M., & Chadwick, G. L. (2004). Protecting study volunteers in research: A manual for investigative sites (3rd ed.). Boston, MA: CenterWatch/Thompson Healthcare, Inc.

    Google Scholar 

  • Escobar-Chares, S. L., Tortolero, S. R., Masse, L. C., Watson, K. B., & Fulton, J. E. (2002). Recruiting and retaining minority women: Findings from the Women on the Move study. Ethnicity and Disease, 12(2), 242–251.

    PubMed  Google Scholar 

  • Faugier, J., & Sargeant, M. (1997). Sampling hard to reach populations. Journal of Advanced Nursing, 26(4), 790–797.

    Article  PubMed  CAS  Google Scholar 

  • Hammett, T. M., Mason, T. H., Joanis, C. L., Foster, S. E., Harmon, P., Robles, R. R., et al. (2000). Acceptability of formulations and application methods for vaginal microbicides among drug-involved women: Results of product trials in three cities. Sexually Transmitted Diseases, 27(2), 119–126.

    Article  PubMed  CAS  Google Scholar 

  • Hammett, T. M., Norton, G. D., Mason, T. H., Langenbahn, S., Mayer, K. H., Robles, R. R., et al. (2000). Drug-involved women as potential users of vaginal microbicides for HIV and STD prevention: A three-city survey. Journal of Women’s Health and Gender-Based Medicine, 9(10), 1071–1080.

    Article  PubMed  CAS  Google Scholar 

  • Harris, K. J., Ahluwalia, J. S., Catley, D., Okuyemi, K. S., Mayo, M. S., & Resnicow, K. (2003). Successful recruitment of minorities into clinical trials: The Kick It at Swope project. Nicotine and Tobacco Research, 5(4), 575–584.

    Article  PubMed  Google Scholar 

  • Holt, B. Y., Morwitz, V. G., Ngo, L., Harrison, P. F., Whaley, K. J., Pettifor, A., et al. (2006). Microbicide preference among young women in California. Journal of Women’s Health, 15(3), 281–294.

    Article  PubMed  Google Scholar 

  • Hung, C. H. (2005). Measuring postpartum stress. Journal of Advanced Nursing, 50(4), 417–424.

    Article  PubMed  Google Scholar 

  • Im, E. O., & Chee, W. (2005). Methodological issues in the recruitment of ethnic minority subjects to research via the Internet: A discussion paper. International Journal of Nursing Studies, 42(8), 923–929.

    Article  PubMed  Google Scholar 

  • Kalsbeek, W. D. (2003). Sampling minority groups in health surveys. Statistics in Medicine, 22(9), 1527–1549.

    Article  PubMed  Google Scholar 

  • Keyzer, J. F., Melnikow, J., Kuppermann, M., Birch, S., Kuenneth, C., Nuovo, J., et al. (2005). Recruitment strategies for minority participation: Challenges and cost lessons from the POWER interview. Ethnicity and Disease, 15(3), 395–406.

    PubMed  Google Scholar 

  • Killien, M., Bigby, J. A., Champion, V., Fernandez-Repollet, E., Jackson, R. D., Kagawa-Singer, M., et al. (2000). Involving minority and underrepresented women in clinical trials: The National Centers of Excellence in Women’s Health. Journal of Women’s Health and Gender-Based Medicine, 9(10), 1061–1070.

    Article  PubMed  CAS  Google Scholar 

  • Lee, S. I., Khang, Y. H., & Lee, M. S. (2004). Women’s attitudes toward mode of delivery in South Korea—A society with high cesarean section rates. Birth, 31(2), 108–116.

    Article  PubMed  Google Scholar 

  • Lewis, C. E., George, V., Fouad, M., Porter, V., Bowen, D., & Urban, N. (1998). Recruitment strategies in the women’s health trial: Feasibility study in minority populations. WHT:FSMP Investigators Group. Women’s Health Trial: Feasibility study in minority populations. Controlled Clinical Trials, 19(5), 461–476.

    Article  PubMed  CAS  Google Scholar 

  • Magnani, R., Sabin K., Saidel T., & Heckathorn D. (2005). Review of sampling hard-to-reach and hidden populations for HIV surveillance. AIDS, 2(19 Suppl), S67–72.

    Article  Google Scholar 

  • Marquez, M. A., Muhs, J. M., Tosomeen, A., Riggs, B. L., & Melton, L. J. III (2003). Costs and strategies in minority recruitment for osteoporosis research. Journal of Bone and Mineral Research, 18(1), 3–8.

    Article  PubMed  Google Scholar 

  • Mason, T. H., Foster, S. E., Finlinson, H. A., Morrow, K. M., Rosen, R., & Vining, S., et al. (2003). Perspectives related to the potential use of vaginal microbicides among drug-involved women: Focus groups in three cities in the United States and Puerto Rico. AIDS and Behavior, 7(4), 339–351.

    Article  PubMed  Google Scholar 

  • Matthews, B. A., Anderson, R. C., & Nattinger, A. B. (2005). Colorectal cancer screening behavior and health insurance status (United States). Cancer Causes and Control, 16(6), 735–742.

    Article  PubMed  Google Scholar 

  • McFarland, W., & Caceres, C. F. (2001). HIV surveillance among men who have sex with men. AIDS, 15(Suppl 3), S23–32.

    Article  PubMed  Google Scholar 

  • McKee, M. B., Picciano, J. F., Roffman, R. A., Swanson, F., & Kalichman, S. C. (2006). Marketing the ‘Sex Check’: Evaluating recruitment strategies for a telephone-based HIV prevention project for gay and bisexual men. AIDS Education and Prevention, 18(2), 116–131.

    Article  PubMed  Google Scholar 

  • McMahon, J. M., Tortu, S., Torres, L., Pouget, E. R., & Hamid, R. (2003). Recruitment of heterosexual couples in public health research: A study protocol. BMC Medical Research Methodology, 3, 24.

    Article  PubMed  Google Scholar 

  • Mills, E., Nixon, S., Singh, S., Dolma, S., Nayyar, A., & Kapoor, S. (2006). Enrolling women into HIV preventive vaccine trials: An ethical imperative but a logistical challenge. Public Library of Science Medicine, 3(3), e94.

    PubMed  Google Scholar 

  • Morrow, K. M., & Costello, T. (2004). HIV, STD and hepatitis prevention among women in methadone maintenance: A qualitative and quantitative needs assessment. AIDS Care, 16(4), 426–433.

    Article  PubMed  CAS  Google Scholar 

  • Morrow , K. M., Fava, J. L., Rosen, R. K., Christensen, A. L., Vargas, S., & Barroso, C. (in press). Willingness to Use Microbicides Varies by Race/Ethnicity, Experience with Prevention Products, and Partner Type. Health Psychology.

  • National Institutes of Health. (2003). Outreach notebook for the inclusion, recruitment and retention of women and minority subjects in clinical research [NIH Publication No. 03–7036]: US Department of Health and Human Services.

  • National Institutes of Health. (2005). New findings on the willingness of minorities to participate in health research. Retrieved May 15, 2006, from http://www.nih.gov/news/pr/dec2005/cc-06.htm.

  • Penrod, J., Preston, D. B., Cain, R. E., & Starks, M. T. (2003). A discussion of chain referral as a method of sampling hard-to-reach populations. Journal of Transcultural Nursing, 14(2), 100–107.

    Article  PubMed  Google Scholar 

  • Promtussananon, S., & Peltzer, K. (2005). Perceptions of tuberculosis: Attributions of cause, suggested means of risk reduction, and preferred treatment in the Limpopo province, South Africa. Journal of Health, Population, and Nutrition, 23(1), 74–81.

    PubMed  Google Scholar 

  • Putzke, J. D., Hicken, B. L., & Richards, J. S. (2002). Race: Predictor versus proxy variable? Outcomes after spinal cord injury. Archives of Physical Medicine and Rehabilitation, 83(11), 1603–1611.

    Article  PubMed  Google Scholar 

  • Ramirez-Valles, J., Heckathorn, D. D., Vazquez, R., Diaz, R. M., & Campbell, R. T. (2005). From networks to populations: The development and application of respondent-driven sampling among IDUs and Latino gay men. AIDS and Behavior, 9(4), 387–402.

    Article  PubMed  Google Scholar 

  • Rodriguez, M. D., Rodriguez, J., & Davis, M. (2006). Recruitment of first-generation Latinos in a rural community: The essential nature of personal contact. Family Process, 45(1), 87–100.

    Article  PubMed  Google Scholar 

  • Rogers, S. N., O’Donnell, J. P., Williams-Hewitt, S., Christensen, J. C., & Lowe, D. (2006). Health-related quality of life measured by the UW-QoL–Reference values from a general dental practice. Oral Oncology, 42, 281–287.

    Article  PubMed  CAS  Google Scholar 

  • Story, M., Sherwood, N. E., Obarzanek, E., Beech, B. M., Baranowski, J. C., Thompson, N. S., et al. (2003). Recruitment of African–American pre-adolescent girls into an obesity prevention trial: The GEMS pilot studies. Ethnicity and Disease, 13(1 Suppl 1), S78–87.

    PubMed  Google Scholar 

  • US Census Bureau. (2005, May 9, 2006). Table 3: Annual Estimates of the Population by Sex, Race and Hispanic or Latino Origin for the United States: April 1, 2000 to July 1, 2005. Retrieved 2006, May 22, from http://www.census.gov/popest/national/asrh/NC-EST2005-srh.html.

  • Watters, J. K., & Biernacki, P. (1989). Targeted sampling: Options for the study of hidden populations. Social Problems, 36(4), 416–430.

    Google Scholar 

  • Weeks, M. R., Mosack, K. E., Abbott, M., Sylla, L. N., Valdes, B., & Prince, M. (2004). Microbicide acceptability among high-risk urban U.S. women: Experiences and perceptions of sexually transmitted HIV prevention. Sexually Transmitted Diseases, 31(11), 682–690.

    Article  PubMed  Google Scholar 

  • Wilson, K. M., & Orians, C. E. (2005). Considerations in recruiting underscreened women to focus groups on screening for cervical cancer. Health Promotion Practice, 6(4), 379–384.

    Article  PubMed  Google Scholar 

  • Wisdom, K., Neighbors, K., Williams, V. H., Havstad, S. L., & Tilley, B. C. (2002). Recruitment of African Americans with Type 2 diabetes to a randomized controlled trial using three sources. Ethnicity and Health, 7(4), 267–278.

    Article  PubMed  Google Scholar 

  • Yancey, A. K., Ortega, A. N., & Kumanyika, S. K. (2006). Effective recruitment and retention of minority research participants. Annual Review of Public Health, 27, 1–28.

    Article  PubMed  Google Scholar 

  • Young, J. B., Robinson, M., Chell, S., Sanderson, D., Chaplin, S., Burns, E., et al. (2005). A whole system study of intermediate care services for older people. Age and Ageing, 34(6), 577–583.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

The National Institutes of Mental Health (NIMH) Grant R01MH64455 funded this work. We would like to thank the following people for their contributions: Hilda Castillo, Allison Cohn, Michelle Gomez, Alyssa Israel, Luz Lopez, Angela Martinez, Mayra Morales, C. Teal Pedlow, and Andronike Tsamas, research staff; Lawrence Severy and Cynthia Woodsong, consultants; Susan Cu-Uvin, Kenneth H. Mayer, and Patricia Symonds, co-investigators. We would also like to thank the women who participated in the study and all the community-based organizations who collaborated with us to facilitate recruitment efforts. Anna L. Christensen is now at Johns Hopkins Bloomberg School of Public Health. Lawrence Shulman is now living in El Paso, TX, and working part-time as a researcher/consultant.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Kathleen M. Morrow.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Morrow, K.M., Vargas, S., Rosen, R.K. et al. The Utility of Non-proportional Quota Sampling for Recruiting At-risk Women for Microbicide Research. AIDS Behav 11, 586–595 (2007). https://doi.org/10.1007/s10461-007-9213-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10461-007-9213-z

Keywords

Navigation