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Primary Rhabdomyosarcoma of the Breast in a 13-Year-Old Girl: Report of a Case

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Abstract

We report a case of primary alveolar rhabdomyosarcoma of the breast in a 13-year-old Japanese girl. The patient initially presented with a 13 × 8-cm mass in her left breast, which was diagnosed as alveolar rhabdomyosarcoma after an excisional biopsy. Genetic expression of the tumor revealed t(2;13)(q35–37;q14). She underwent modified radical mastectomy (Bt + Ax) and nine lymph nodes were found to be involved. Systemic examinations showed multiple bone and lung metastases 2 weeks after her operation. Despite chemotherapy with doxorubicin, ifosfamide, and actinomycin D, which resulted in remission for 6 months, she died of the disease 8 months after surgery.

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Authors and Affiliations

  1. Department of Breast and Endocrine Surgery, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan

    Hiroko Nogi, Kazumi Kawase, Isao Tabei, Yasuo Toriumi & Ken Uchida

  2. Department of Clinical Oncology, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan

    Tadashi Kobayashi

  3. Department of Pathology, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan

    Masafumi Suzuki & Makio Kawakami

  4. Department of Respiratory Surgery, Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan

    Toshiaki Morikawa

Authors
  1. Hiroko Nogi
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  2. Tadashi Kobayashi
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  3. Kazumi Kawase
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  4. Isao Tabei
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  5. Yasuo Toriumi
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  6. Masafumi Suzuki
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  7. Makio Kawakami
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  8. Toshiaki Morikawa
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  9. Ken Uchida
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Nogi, H., Kobayashi, T., Kawase, K. et al. Primary Rhabdomyosarcoma of the Breast in a 13-Year-Old Girl: Report of a Case. Surg Today 37, 38–42 (2007). https://doi.org/10.1007/s00595-006-3326-2

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  • DOI: https://doi.org/10.1007/s00595-006-3326-2

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