Abstract
Here we describe a detailed analysis of the expression of neurochondrin (ncdn) in the developing and adult mouse brain. Ncdn is first expressed in the hindbrain and spinal cord at embryonic day 10.5 (E10.5) followed by expression in the midbrain at E11.5. By E18 ncdn is also expressed in the diencephalon and telencephalon. However, strongest expression is still observed in the hindbrain. In adults, the expression in the forebrain is as strong as in the hindbrain. Ncdn is highly expressed in the hippocampus, piriform cortex, septum, amygdaloid complex, medial geniculate nucleus, inferior colliculus, cerebellar nuclei and the nuclei of the Vth, VIIth, and XIIth cranial nerves.
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Acknowledgements
We thank S. Pirrung, K. Mayer, I. Rodionova and I. Petrova for the expert technical assistance. For the ISH probe we thank Key Maruyama (Okazaki, Japan). This study was supported by BMBF and EU (Eumorphia) for W. Wurst.
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Edited by B. Herrmann
R. Istvánffy and D.M. Vogt Weisenhorn contributed equally to this paper
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Istvánffy, R., Vogt Weisenhorn, D.M., Floss, T. et al. Expression of neurochondrin in the developing and adult mouse brain. Dev Genes Evol 214, 206–209 (2004). https://doi.org/10.1007/s00427-004-0396-2
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DOI: https://doi.org/10.1007/s00427-004-0396-2