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Paternity testing using Y-STR haplotypes: assigning a probability for paternity in cases of mutations

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International Journal of Legal Medicine Aims and scope Submit manuscript

Abstract

In parentage testing with male children, Y-chromosomal STR evidence is gaining more and more importance. In some cases, multilocus haplotypes of related persons can differ at a single locus due to a mutation. In this work, a likelihood approach is presented for the calculation of a probability for paternity under consideration of a single mutation event on the Y-chromosome. The new methodology is applied to two case examples.

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Authors and Affiliations

  1. Institute of Legal Medicine, Ludwigs-Maximilians-Universität, Frauenlobstrasse 7a, 80337 München, Germany e-mail: burkhard.rolf@rechts.med.uni-muenchen.de, , , , , , DE

    B. Rolf & W. Keil

  2. Institute of Legal Medicine, Westfälische-Wilhelms-Universität Münster, Von-Esmarch-Strasse 62, 48149 Münster, Germany, , , , , , DE

    B. Brinkmann

  3. Institute of Legal Medicine, Humboldt-Universität, Hannoversche Strasse 6, 10115 Berlin, Germany, , , , , , DE

    L. Roewer

  4. Institut für Medizinischen Biometrie, Informatik und Epidemiologie, Rheinische Friedrich-Wilhelms-Universität, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany, , , , , , DE

    R. Fimmers

Authors
  1. B. Rolf
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  2. W. Keil
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  3. B. Brinkmann
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  4. L. Roewer
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  5. R. Fimmers
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Additional information

Received: 10 April 2000 / Accepted: 2 December 2000

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Rolf, B., Keil, W., Brinkmann, B. et al. Paternity testing using Y-STR haplotypes: assigning a probability for paternity in cases of mutations. Int J Leg Med 115, 12–15 (2001). https://doi.org/10.1007/s004140000201

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  • DOI: https://doi.org/10.1007/s004140000201

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