Skip to main content
SpringerLink
Log in

Collateral Damage: Depressive Symptoms in the Partners of COPD Patients

  • Published:
Lung Aims and scope Submit manuscript

Abstract

Background

Depression is a frequent comorbidity in COPD patients and is associated with greater physical impairment, increased health-care utilization, and worse outcomes. The presence of depressive symptoms in the partners of COPD patients has not been evaluated.

Methods

We evaluated the partners of 230 consecutive COPD patients included in a prospective study. Depressive symptoms were evaluated using Beck’s Depression Inventory (BDI) on the first day of admission for COPD exacerbation. Patients were followed-up for 1 year.

Results

Significant depressive symptoms were present in 39.6 % of the COPD patients and in 40.9 % of their partners. Beck scores were higher in the partners of patients with severe airflow obstruction and in those with ≥2 exacerbations and ≥1 hospitalizations for COPD exacerbation during the 1-year follow-up. The BDI score of the patients’ partners was significantly correlated with the BDI score of the COPD patients (r s = 0.422). In multivariate analysis, depressive symptoms in the COPD patients were an independent predictor of depressive symptoms in their partners (OR 4.136, 95 % CI 1.991–8.594; p < 0.001).

Conclusions

A large proportion of the partners of COPD patients present significant depressive symptoms. The identification of those patients and their partners represents a possible target for intervention.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

Abbreviations

AECOPD:

Acute exacerbations of chronic obstructive pulmonary disease

BDI:

Beck’s depression inventory

CCIS:

Charlson’s comorbidity index score

CI:

Confidence interval

COPD:

Chronic obstructive pulmonary disease

FEV1 :

Forced expiratory volume in 1 second

FiO2 :

Fraction of inhaled oxygen

OR:

Odds ratio

PO2 :

Partial pressure of oxygen

References

  1. Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2011. Available at http://www.goldcopd.org (Accessed on 29 Apr 2012)

  2. Yohannes AM, Willgoss TG, Baldwin RC, Connolly MJ (2010) Depression and anxiety in chronic heart failure and chronic obstructive pulmonary disease: prevalence, relevance, clinical implications and management principles. Int J Geriatr Psychiatry 25(12):1209–1221. doi:10.1002/gps.2463

    Article  CAS  PubMed  Google Scholar 

  3. Maurer J, Rebbapragada V, Borson S, Goldstein R, Kunik ME, Yohannes AM, Hanania NA (2008) Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest 134(4 Suppl):43S–56S. doi:10.1378/chest.08-0342

    Article  PubMed Central  PubMed  Google Scholar 

  4. van Manen JG, Bindels PJ, Dekker FW, IJzermans CJ, van der Zee JS, Schade E (2002) Risk of depression in patients with chronic obstructive pulmonary disease and its determinants. Thorax 57(5):412–416

    Article  PubMed Central  PubMed  Google Scholar 

  5. Papaioannou AI, Bartziokas K, Tsikrika S, Karakontaki F, Kastanakis E, Banya W, Haniotou A, Papiris S, Loukides S, Polychronopoulos V, Kostikas K (2013) The impact of depressive symptoms on recovery and outcome of hospitalised COPD exacerbations. Eur Respir J 41(4):815–823. doi:10.1183/09031936.00013112

    Article  PubMed  Google Scholar 

  6. Halpern MT, Polzin J, Higashi MK, Bakst A (2004) The workplace impact of acute exacerbations of chronic bronchitis (AECB): a literature review. COPD 1(2):249–254

    Article  PubMed  Google Scholar 

  7. Pochard F, Azoulay E, Chevret S, Lemaire F, Hubert P, Canoui P, Grassin M, Zittoun R, le Gall JR, Dhainaut JF, Schlemmer B (2001) Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity. Crit Care Med 29(10):1893–1897

    Article  CAS  PubMed  Google Scholar 

  8. Fagnano M, Berkman E, Wiesenthal E, Butz A, Halterman JS (2012) Depression among caregivers of children with asthma and its impact on communication with health care providers. Public Health 126(12):1051–1057. doi:10.1016/j.puhe.2012.08.007

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  9. Anaforoglu I, Ramazanogullari I, Algun E, Kutanis R (2012) Depression, anxiety and quality of life of family caregivers of patients with type 2 diabetes. Med Princ Pract 21(4):360–365. doi:10.1159/000334622

    Article  PubMed  Google Scholar 

  10. Cipolletta S, Shams M, Tonello F, Pruneddu A (2013) Caregivers of patients with cancer: anxiety, depression and distribution of dependency. Psychooncology 22(1):133–139. doi:10.1002/pon.2081

    Article  PubMed  Google Scholar 

  11. Al-Gamal E, Yorke J (2014) Perceived breathlessness and psychological distress among patients with chronic obstructive pulmonary disease and their spouses. Nurs Health Sci 16(1):103–111. doi:10.1111/nhs.12073

    Article  PubMed  Google Scholar 

  12. Meier C, Bodenmann G, Morgeli H, Jenewein J (2011) Dyadic coping, quality of life, and psychological distress among chronic obstructive pulmonary disease patients and their partners. Int J Chron Obstr Pulmon Dis 6:583–596. doi:10.2147/copd.s24508

    Article  Google Scholar 

  13. Richter P, Werner J, Heerlein A, Kraus A, Sauer H (1998) On the validity of the Beck Depression Inventory. a review. Psychopathology 31(3):160–168

    Article  CAS  PubMed  Google Scholar 

  14. Beck AT, Epstein N, Brown G, Steer RA (1988) An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol 56(6):893–897

    Article  CAS  PubMed  Google Scholar 

  15. Vestbo J, Hurd SS, Rodriguez-Roisin R (2012) The 2011 revision of the global strategy for the diagnosis, management and prevention of COPD (GOLD)–why and what? Clin Respir J 6(4):208–214. doi:10.1111/crj.12002

    Article  PubMed  Google Scholar 

  16. Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373–383

    Article  CAS  PubMed  Google Scholar 

  17. Hurst JR, Vestbo J, Anzueto A, Locantore N, Mullerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA, Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) Investigators (2010) Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med 363(12):1128–1138. doi:10.1056/NEJMoa0909883

    Article  CAS  PubMed  Google Scholar 

  18. Parish JM, Lyng PJ (2003) Quality of life in bed partners of patients with obstructive sleep apnea or hypopnea after treatment with continuous positive airway pressure. Chest 124(3):942–947

    Article  PubMed  Google Scholar 

  19. Jones PW (2007) Activity limitation and quality of life in COPD. COPD 4(3):273–278. doi:10.1080/15412550701480265

    Article  PubMed  Google Scholar 

  20. Bourbeau J (2009) Activities of life: the COPD patient. COPD 6(3):192–200

    Article  PubMed  Google Scholar 

  21. Soler-Cataluna JJ, Martinez-Garcia MA, Roman Sanchez P, Salcedo E, Navarro M, Ochando R (2005) Severe acute exacerbations and mortality in patients with chronic obstructive pulmonary disease. Thorax 60(11):925–931. doi:10.1136/thx.2005.040527

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  22. Dahlen I, Janson C (2002) Anxiety and depression are related to the outcome of emergency treatment in patients with obstructive pulmonary disease. Chest 122(5):1633–1637

    Article  PubMed  Google Scholar 

  23. Toy EL, Gallagher KF, Stanley EL, Swensen AR, Duh MS (2010) The economic impact of exacerbations of chronic obstructive pulmonary disease and exacerbation definition: a review. COPD 7(3):214–228. doi:10.3109/15412555.2010.481697

    Article  PubMed  Google Scholar 

  24. Quint JK, Baghai-Ravary R, Donaldson GC, Wedzicha JA (2008) Relationship between depression and exacerbations in COPD. Eur Respir J 32(1):53–60. doi:10.1183/09031936.00120107

    Article  CAS  PubMed  Google Scholar 

Download references

Conflict of interest

None of the other authors has any conflict of interest related to the present manuscript. There was no funding for the present study.

Author information

Authors and Affiliations

  1. 3rd Respiratory Medicine Department, Sismanogleion General Hospital, Sismanogleiou 1 Str, 15126, Athens, Greece

    Andriana I. Papaioannou, Stamatoula Tsikrika, Foteini Karakontaki, Emmanouil Kastanakis, Filia Diamantea & Vlassis Polychronopoulos

  2. Respiratory Medicine Department, Amalia Fleming General Hospital, Pigis 2 & Zaimi Str, 15127, Athens, Greece

    Konstantinos Bartziokas & Aikaterini Haniotou

  3. 2nd Respiratory Medicine Department, University of Athens Medical School, Rimini 1, 12462, Athens, Greece

    Spyros Papiris, Stelios Loukides & Konstantinos Kostikas

  4. Stamouli 3, 43100, Karditsa, Greece

    Konstantinos Kostikas

Authors
  1. Andriana I. Papaioannou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Stamatoula Tsikrika
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Konstantinos Bartziokas
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Foteini Karakontaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Emmanouil Kastanakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Filia Diamantea
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Aikaterini Haniotou
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Spyros Papiris
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Vlassis Polychronopoulos
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Stelios Loukides
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Konstantinos Kostikas
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Konstantinos Kostikas.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Papaioannou, A.I., Tsikrika, S., Bartziokas, K. et al. Collateral Damage: Depressive Symptoms in the Partners of COPD Patients. Lung 192, 519–524 (2014). https://doi.org/10.1007/s00408-014-9595-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00408-014-9595-4

Keywords

Search

Navigation