Abstract
Aim
This study aimed to compare the pregnancy outcome at maternal age 35 years and above with those aged between 20 and 34 years in a high-income developing country.
Methods
In this prospective study, pregnant women that delivered at Al-Ain Hospital from the 1st April 2009 till 30th September 2009 were included. The obstetrical and perinatal outcome of mothers aged between 20 and 34 years and those aged 35 years old and above was compared.
Results
There were a total of 888 patients. 699/888 (78.7%) were aged between 20 and 34 years and 189 (21.3%) were aged 35 years and above. Advanced maternal age was significantly associated with a higher incidence of type II diabetes mellitus (p = 0001), hypothyroidism (p = 0.02), history of miscarriages (p = 0.0001), GDM (p = 0.0001), placenta previa p = 0.04, induction of labor (p = 0.04), and Cesarean section (p = 0.009).
Conclusion
Pregnant women at 35 years and above have higher incidence of gestational diabetes mellitus, placenta previa, and operative delivery. However, perinatal outcome are comparable to younger mothers.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Heffner LJ (2004) Advanced maternal age—how old is too old? N Engl J Med 351:1927–1929
Green KE, Smith DE (2007) Change and continuity: childbirth and parenting across three generations of women in the United Arab Emirates. Child Care Health Dev 33:266–274
El-shalakani M (1992) Estimation of parity progression ratios from survey data on birth intervals in Egypt. Egypt Popul Fam Plann Rev 26:67–82
Delpishe A, Brabin L, Attia E, Brabin BJ (2008) Pregnancy late in life: a hospital-based study of birth outcomes. J Womens Health (Larchmt) 17:965–970
Nassar AH, Usta IM (2009) Advanced maternal age. Part II: long-term consequences. Am J Perinatol 26:107–112
Jahan MK, Shafiquzzaman M, Nahar K, Rahman M, Sultana N, Rahman MM, Begum R (2009) Outcome of pregnancy in women 35 years of age and above. Mymensingh Med J 18(1):7–12
Yogev Y, Melamed N, Bardin R, Tenenbaum-Gavish K, Ben-Shitrit G, Ben-Haroush A (2010) Pregnancy outcome at extremely advanced maternal age. Am J Obstet Gynecol 203:558e1–558e7
Jahromi BN, Husseini Z (2008) Pregnancy outcome at maternal age 40 and older. Taiwan J Obstet Gynecol 47:318–321
Diejomaoh MF, Al-Shamali IA, Al-Kandari F, Al-Qenae M, Mohd AT (2006) The reproductive performance of women at 40 years and over. Eur J Obstet Gynecol Reprod Biol 126:33–38
Oboro VO, Dare FO (2006) Pregnancy outcome in nulliparous women aged 35 or older. West Afr J Med 25:65–68
Carter AO, Saadi HF, Reed RL, Dunn EV (2004) Assessment of obesity, lifestyle, and reproductive health needs of female citizens of Al Ain, United Arab Emirates. J Health Popul Nutr 22:75–83
Usta IM, Zoorob D, Abu-Musa A, Naassan G, Nassar AH (2008) Obstetric outcome of teenage pregnancies compared with adult pregnancies. Acta Obstet Gynecol Scand 87(2):178–183
Agarwal MM, Hughes PF, Punnose J, Ezimokhai M, Thomas L (2001) Gestational diabetes screening of a multiethnic, high-risk population using glycated proteins. Diabetes Res Clin Pract 51:67–73
Sabri S, Bener A, Eapen V, Abu Zeid MS, Al-Mazrouei AM, Singh J (2004) Some risk factors for hypertension in the United Arab Emirates. East Mediterr Health J 10:610–619
Kadiyala R, Peter R, Okosieme OE (2010) Thyroid dysfunction in patients with diabetes: clinical implications and screening strategies. Int J Clin Pract 64:1130–1139
Cleary-Goldman J, Malone FD, Vidaver J, Ball RH, Nyberg DA, Comstock CH et al (2005) Impact of maternal age on obstetric outcome. Obstet Gynecol 105:983–990
Warburton D (1987) Reproductive loss: how much is preventable? N Engl J Med 316:158–160
Coste J, Job-Spira N, Fernandez H (1991) Risk factors for spontaneous abortion: a case-control study in France. Hum Reprod 6:1332–1337
Oya A, Nakai A, Miyake H, Kawabata I, Takeshita T (2008) Risk factors for peripartum blood transfusion in women with placenta previa: a retrospective analysis. J Nippon Med Sch 75:146–151
Gilliam M, Rosenberg D, Davis F (2002) The likelihood of placenta previa with greater number of cesarean deliveries and higher parity. Obstet Gynecol 99:976–980
Shechter Y, Levy A, Wiznitzer A, Zlotnik A, Sheiner E (2010) Obstetric complications in grand and great grand multiparous women. J Matern Fetal Neonatal Med 23:1211–1217
Rizk DE, Khalfan M, Ezimokhai M (2001) Obstetric outcome in grand multipara in the United Arab Emirates. A case control study. Arch Gynecol Obstet 264:194–198
Weerasekera DS, Udugama SG (2003) Pregnancy at 40 and over: a case-control study in a developing country. J Obstet Gynaecol 23:625–627
Chien LY, Tai CJ, Chu KH, Ko YL, Chiu YC (2007) The number of Baby Friendly hospital practices experienced by mothers is positively associated with breastfeeding: a questionnaire survey. Int J Nurs Stud 44:1138–1146
Huang L, Sauve R, Birkett N, Fergusson D (2008) Carl van Walraven MD MScMaternal age and risk of stillbirth: a systematic review. CMAJ 178:165–172
Delpisheh A, Brabin L, Attia E, Brabin BJ (2008) Pregnancy late in life: a hospital-based study of birth outcomes. J Womens Health (Larchmt) 17(6):965–970
Acknowledgments
The authors are grateful to Mrs. Flora Dimaculangan, research nurse at the Faculty of Medicine and Health Sciences, United Arab University for her valuable help and organization.
Conflict of interest
The authors declare no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
AlShami, H.A.A., Kadasne, A.R., Khalfan, M. et al. Pregnancy outcome in late maternal age in a high-income developing country. Arch Gynecol Obstet 284, 1113–1116 (2011). https://doi.org/10.1007/s00404-010-1821-6
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00404-010-1821-6