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Diet and prostate cancer prevention

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Abstract

Purpose

To evaluate the present human-based evidence that diet is related to the risk and outcome of prostate cancer.

Methods

Review of major case–control and cohort studies, and experimental trials evaluating the effect of diet or dietary constituents on the risk of prostate cancer.

Results

Although non-experimental studies have suggested several dimensions of diet and several dietary components as related to risk and outcome of prostate cancer, the results of these studies are inconsistent. There is limited evidence that a diet that emphasizes plant products is associated with diminished risk of prostate cancer and of aggressive prostate cancer.

Conclusion

The non-experimental epidemiologic evidence that has now accrued justifies trials of dietary intervention for those at elevated risk of prostate cancer.

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Acknowledgments

Manuscript supported by National Cancer Institute grant R01-CA132951, “Diet change among prostate cancer patients under expectant management.”

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The author declares that he has no conflict of interest.

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Correspondence to James R. Marshall.

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Marshall, J.R. Diet and prostate cancer prevention. World J Urol 30, 157–165 (2012). https://doi.org/10.1007/s00345-011-0810-0

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