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Efficacy of 1-day prophylaxis medication with fluoroquinolone for prostate biopsy

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Abstract

A prospective, randomized trial in which 236 patients received oral levofloxacin, either at 600 mg/day for 1 day (n=124) or 300 mg/day for 3 days (n=112). Urinalysis, plasma white blood cell count (WBC) (per mm3), and C reactive protein (CRP) (mg/dl) levels were checked before prostate biopsy (PBX), on the day after PBX, and on the seventh day after PBX. Two patients (1.61%) who received 600 mg for 1 day and 2 patients (1.79%) who received 300 mg for 3 days had febrile infectious complications. There was no statistically significant difference between levofloxacin at 600 mg for 1 day and levofloxacin at 300 mg for 3 days regarding the elevation of WBC and CRP. We can perform PBX safely with levofloxacin at 600 mg for 1 day as prophylaxis and recommend this method from the point of view of the decrease of antibiotic-resistant strains.

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References

  1. Aron M, Rajeev TP, Gupta NP (2000) Antibiotic prophylaxis for transrectal needle biopsy of the prostate: a randomized controlled study. BJU Int 85:682–685

    Article  PubMed  CAS  Google Scholar 

  2. Bishop D, Oliver J (1977) A study of transrectal aspiration biopsies of the prostate, with particular regard to prognostic evaluation. J Urol 117:313–315

    PubMed  CAS  Google Scholar 

  3. Brewster SF, MacGowan AP, Gingell JC (1995) Antimicrobial prophylaxis for transrectal prostatic biopsy: a prospective randomized trial of cefuroxime versus piperacillin/tazobactam. Br J Urol 76:351–354

    Article  PubMed  CAS  Google Scholar 

  4. Carey JM, Korman HJ (2001) Transrectal ultrasound guided biopsy of the prostate. Do enemas decrease clinically significant complications? J Urol 166:82–85

    Article  PubMed  CAS  Google Scholar 

  5. Onder AU, Yaycioglu O, Ataus S, Gul U, Demirkesen O, Yalcin V, Solok V (2003) Transition zone biopsy and prediction of extraprostatic extension at radical prostatectomy. Int J Urol 10:302–308

    Article  PubMed  Google Scholar 

  6. Cormio L, Berardi B, Callea A, Fiorentino N, Sblendorio D, Zizzi V, Traficante A (2002) Antimicrobial prophylaxis for transrectal prostatic biopsy: a prospective study of ciprofloxacin vs piperacillin/tazobactam. BJU Int 90:700–702

    Article  PubMed  CAS  Google Scholar 

  7. Crawford ED, Haynes AL Jr, Story MW, Borden TA (1982) Prevention of urinary tract infection and sepsis following transrectal prostatic biopsy. J Urol 127:449–451

    PubMed  CAS  Google Scholar 

  8. Davis R, Bryson HM (1994) Levofloxacin. A review of its antibacterial activity, pharmacokinetics, and therapeutic efficacy. Drugs 48:132

    Article  Google Scholar 

  9. Desmond PM, Clark J, Thompson IM, Zeidman EJ, Mueller EJ (1993) Morbidity with contemporary prostate biopsy. J Urol 150:1425–1426

    PubMed  CAS  Google Scholar 

  10. Drusano GL, Preston SL, Van Guilder M (2000) A population pharmacokinetic analysis of the penetration of the prostate by levofloxacin. Antimicrob Agents Chemother 44:2046–2051

    Article  PubMed  CAS  Google Scholar 

  11. Fournier G, Valeri A, Mangin P, Cussenot O (2004) Prostate cancer: diagnosis and staging. Ann Urol (Paris) 38:207–224

    CAS  Google Scholar 

  12. Fujimoto N, Harada S, Sato H, Akasaka S, Nomura M, Yamada Y, Ueno Y, Matsumoto T (2004) Screening for prostate cancer in Yahata, Kitakyushu. J UOEH 26:239–244

    PubMed  Google Scholar 

  13. Griffith BC, Morey AF, Ali-Khan MM, Canby-Hagino E, Foley JP, Rozanski TA (2002) Single dose levofloxacin prophylaxis for prostate biopsy in patients at low risk. J Urol 168:1021–1023

    Article  PubMed  CAS  Google Scholar 

  14. Isen K, Kupeli B, Sinik Z, Sozen S, Bozkirli I (1999) Antibiotic prophylaxis for transrectal biopsy of the prostate: a prospective randomized study of the prophylactic use of single dose oral fluoroquinolone versus trimethoprim-sulfamethoxazole. Int Urol Nephrol 31:491–495

    Article  PubMed  CAS  Google Scholar 

  15. Kapoor DA, Klimberg IW, Malek GH, Wegenke JD, Cox CE, Patterson AL, Graam E, Echols RM, Whalen E, Kowalsky SF (1998) Single-dose oral ciprofloxacin versus placebo for prophylaxis during transrectal prostate biopsy. Urology 52:552–558

    Article  PubMed  CAS  Google Scholar 

  16. Larsen EH, Gasser TC, Madsen PO (1986) Antimicrobial prophylaxis in urologic surgery. Urol Clin North Am 4:591–604

    Google Scholar 

  17. Lindert KA, Kabalin JN, Terris MK (2000) Bacteremia and bacteriuria after transrectal ultrasound guided prostate biopsy. J Urol 164:76–80

    Article  PubMed  CAS  Google Scholar 

  18. Onder AU, Yaycioglu O, Ataus S, Gul U, Demirkesen O, Yalcin V, Solok V (2003) Transition zone biopsy and prediction of extraprostatic extension at radical prostatectomy. Int J Urol 10:302–308

    Article  PubMed  Google Scholar 

  19. Packer MG, Russo P, Fair WR (1984) Prophylactic antibiotics and Foley catheter use in transperineal needle biopsy of the prostate. J Urol 131:687–689

    PubMed  CAS  Google Scholar 

  20. Sieber PR, Rommel FM, Agusta VE, Breslin JA, Huffnagle HW, Harpster LE (1997) Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy. J Urol 157:2199–2200

    Article  PubMed  CAS  Google Scholar 

  21. Turner B, Warner J, Rhamy R (1980) Prostatic needle examination. South Med J 73:183–184

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Division of Urology, Department of Organs Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-Cho, Chuo-Ku, Kobe, 650-0017, Japan

    Katsumi Shigemura, Kazushi Tanaka, Sadao Kamidono, Yuzo Nakano, Soichi Arakawa & Masato Fujisawa

  2. Department of Urology, Gifu University School of Medicine, Gifu, Japan

    Mitsuru Yasuda, Satoshi Ishihara & Takashi Deguchi

  3. Department of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan

    Tetsuro Muratani & Tetsuro Matsumoto

Authors
  1. Katsumi Shigemura
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  2. Kazushi Tanaka
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  3. Mitsuru Yasuda
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  4. Satoshi Ishihara
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  5. Tetsuro Muratani
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  6. Takashi Deguchi
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  7. Tetsuro Matsumoto
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  8. Sadao Kamidono
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  9. Yuzo Nakano
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  10. Soichi Arakawa
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  11. Masato Fujisawa
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Corresponding author

Correspondence to Soichi Arakawa.

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Shigemura, K., Tanaka, K., Yasuda, M. et al. Efficacy of 1-day prophylaxis medication with fluoroquinolone for prostate biopsy. World J Urol 23, 356–360 (2005). https://doi.org/10.1007/s00345-005-0024-4

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  • DOI: https://doi.org/10.1007/s00345-005-0024-4

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