Abstract
Low-field extremity magnetic resonance imaging (MRI) has been developed as an alternative method for detecting inflammatory changes and structural damage associated with rheumatoid arthritis (RA). Studies have shown that extremity MRI is able to predict future joint damage in patients with early RA and is more sensitive than conventional radiography at detecting joint erosions. This report uses four different cases to illustrate how extremity MRI can be used to monitor disease activity and inform treatment decisions during the management of RA in the routine clinical practice setting.
References
Freeston JE, Conaghan PG, Dass S, Vital E, Hensor EM, Stewart SP et al (2007) Does extremity-MRI improve erosion detection in severely damaged joints? A study of long-standing rheumatoid arthritis using three imaging modalities. Ann Rheum Dis 66:1538–1540. doi:10.1136/ard.2007.074708
Schiff MH, Hobbs KF, Gensler T, Keenan GF (2007) A retrospective analysis of low-field strength magnetic resonance imaging and the management of patients with rheumatoid arthritis. Curr Med Res Opin 23:961–968. doi:10.1185/030079907X178892
Lindegaard HM, Vallo J, Horslev-Petersen K, Junker P, Ostergaard M (2006) Low-cost, low-field dedicated extremity magnetic resonance imaging in early rheumatoid arthritis: a 1-year follow-up study. Ann Rheum Dis 65:1208–1212. doi:10.1136/ard.2005.049213
Chen TS, Crues JV 3rd, Ali M, Troum OM (2006) Magnetic resonance imaging is more sensitive than radiographs in detecting change in size of erosions in rheumatoid arthritis. J Rheumatol 33:1957–1967
Crues JV, Shellock FG, Dardashti S, James TW, Troum OM (2004) Identification of wrist and metacarpophalangeal joint erosions using a portable magnetic resonance imaging system compared to conventional radiographs. J Rheumatol 31:676–685
Aletaha D, Smolen JS (2002) The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses. Rheumatology (Oxford) 41:1367–1374. doi:10.1093/rheumatology/41.12.1367
Gaylis NB, Needell SD, Rudensky D (2007) Comparison of in-office magnetic resonance imaging versus conventional radiography in detecting changes in erosions after one year of infliximab therapy in patients with rheumatoid arthritis. Mod Rheumatol 17:273–278. doi:10.1007/s10165-007-0591-x
Duer-Jensen A, Vestergaard A, Dohn UM, Ejbjerg B, Hetland ML, Albrecht-Beste E et al (2008) Detection of rheumatoid arthritis bone erosions by two different dedicated extremity MRI units and conventional radiography. Ann Rheum Dis 67:998–1003. doi:10.1136/ard.2007.076026
Acknowledgments
Support for third-party writing assistance for this manuscript, furnished by Neil Anderson, was provided by Genentech, Inc. and Biogen Idec.
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Gaylis, N.B., Needell, S.D. In-office magnetic resonance imaging to monitor responses to therapy in rheumatoid arthritis. Rheumatol Int 30, 269–273 (2009). https://doi.org/10.1007/s00296-009-0927-2
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DOI: https://doi.org/10.1007/s00296-009-0927-2