Skip to main content

Advertisement

Log in

In-office magnetic resonance imaging to monitor responses to therapy in rheumatoid arthritis

  • Case Report
  • Published:
Rheumatology International Aims and scope Submit manuscript

Abstract

Low-field extremity magnetic resonance imaging (MRI) has been developed as an alternative method for detecting inflammatory changes and structural damage associated with rheumatoid arthritis (RA). Studies have shown that extremity MRI is able to predict future joint damage in patients with early RA and is more sensitive than conventional radiography at detecting joint erosions. This report uses four different cases to illustrate how extremity MRI can be used to monitor disease activity and inform treatment decisions during the management of RA in the routine clinical practice setting.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

References

  1. Freeston JE, Conaghan PG, Dass S, Vital E, Hensor EM, Stewart SP et al (2007) Does extremity-MRI improve erosion detection in severely damaged joints? A study of long-standing rheumatoid arthritis using three imaging modalities. Ann Rheum Dis 66:1538–1540. doi:10.1136/ard.2007.074708

    Article  CAS  PubMed  Google Scholar 

  2. Schiff MH, Hobbs KF, Gensler T, Keenan GF (2007) A retrospective analysis of low-field strength magnetic resonance imaging and the management of patients with rheumatoid arthritis. Curr Med Res Opin 23:961–968. doi:10.1185/030079907X178892

    Article  PubMed  Google Scholar 

  3. Lindegaard HM, Vallo J, Horslev-Petersen K, Junker P, Ostergaard M (2006) Low-cost, low-field dedicated extremity magnetic resonance imaging in early rheumatoid arthritis: a 1-year follow-up study. Ann Rheum Dis 65:1208–1212. doi:10.1136/ard.2005.049213

    Article  CAS  PubMed  Google Scholar 

  4. Chen TS, Crues JV 3rd, Ali M, Troum OM (2006) Magnetic resonance imaging is more sensitive than radiographs in detecting change in size of erosions in rheumatoid arthritis. J Rheumatol 33:1957–1967

    PubMed  Google Scholar 

  5. Crues JV, Shellock FG, Dardashti S, James TW, Troum OM (2004) Identification of wrist and metacarpophalangeal joint erosions using a portable magnetic resonance imaging system compared to conventional radiographs. J Rheumatol 31:676–685

    PubMed  Google Scholar 

  6. Aletaha D, Smolen JS (2002) The rheumatoid arthritis patient in the clinic: comparing more than 1,300 consecutive DMARD courses. Rheumatology (Oxford) 41:1367–1374. doi:10.1093/rheumatology/41.12.1367

    Article  CAS  Google Scholar 

  7. Gaylis NB, Needell SD, Rudensky D (2007) Comparison of in-office magnetic resonance imaging versus conventional radiography in detecting changes in erosions after one year of infliximab therapy in patients with rheumatoid arthritis. Mod Rheumatol 17:273–278. doi:10.1007/s10165-007-0591-x

    Article  CAS  PubMed  Google Scholar 

  8. Duer-Jensen A, Vestergaard A, Dohn UM, Ejbjerg B, Hetland ML, Albrecht-Beste E et al (2008) Detection of rheumatoid arthritis bone erosions by two different dedicated extremity MRI units and conventional radiography. Ann Rheum Dis 67:998–1003. doi:10.1136/ard.2007.076026

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

Support for third-party writing assistance for this manuscript, furnished by Neil Anderson, was provided by Genentech, Inc. and Biogen Idec.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Norman B. Gaylis.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gaylis, N.B., Needell, S.D. In-office magnetic resonance imaging to monitor responses to therapy in rheumatoid arthritis. Rheumatol Int 30, 269–273 (2009). https://doi.org/10.1007/s00296-009-0927-2

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00296-009-0927-2

Keywords

Navigation