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Effects of Reduction Mammoplasty on Metabolic Profile and Body Weight

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Abstract

Background

Advanced studies on adipose tissue have established that subcutaneous adipose tissue acts as an endocrine organ to help maintain homeostasis. Based on this information, many plastic surgeons have evaluated the metabolic effects of liposuction because liposuction is the most common surgical procedure in plastic surgery. Liposuction removes a substantial amount of subcutaneous fat from a specific area of the body. Mammoplasty is another procedure that removes a large amount of subcutaneous fat. In this study, the metabolic effects of reduction mammoplasty were evaluated with hemogram, blood glucose, lipid profile, insulin, and insulin resistance tests before and after surgery.

Methods

The study involved 35 patients who underwent reduction mammoplasty between January 2006 and June 2009. All the patients were evaluated with physical examination and their history, height, and weight were obtained. Venous blood samples were collected before, 4 h after, and 3 months after the surgical procedure to evaluate hemogram, blood glucose, insulin, and lipid profiles. The HOMA scores of the patients were calculated. Inferiorly based dermal pedicle, central pedicle, and free nipple graft techniques were used in the operations and all excision materials were sent for histopathological examination.

Results

The mean age of the patients was 39.6 ± 11.6 years. The mean excision volume was 2249 ± 1001 g. Body mass indexes were not significantly different before and 3 months after the surgery (p > 0.05). Blood glucose, LDL, HDL, triglyceride, total cholesterol, hemoglobin, and hematocrit values before and 4 h after the surgery were also different (p < 0.05). However, comparisons with the 3-month postoperative test results revealed no statistically significant differences (p > 0.05) and comparisons of all the measurements showed that insulin levels and HOMA scores were not significantly different (p > 0.05).

Conclusion

The results of the present study showed that reduction mammoplasty operations do not have any positive effects on blood insulin, glucose profile, lipid profile, and body mass index 3 months after the surgery.

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References

  1. Psillakis JM, Cardoso de Oliveira M (1990) History of reduction mammoplasty. In: Goldwyn RM (ed) Reduction mammoplasty, 1st edn. Little, Brown, Boston, pp 1–15

    Google Scholar 

  2. Cruz-Korchin N, Korchin L, Gonzales-Kealan C, Climent C, Morales I (2002) Macromastia: how much of it is fat? Plast Reconstr Surg 109:64–68

    Article  PubMed  Google Scholar 

  3. Emral R (2006) Adiponectin and other cytokines. Türk Klin J Med Sci 26:409–420

    CAS  Google Scholar 

  4. Hong YG, Kim HT, Seo SW, Chang CH, Rhee EJ, Lee WY (2006) Impact of large volume liposuction on serum lipids in orientals: A pilot study. Aesthetic Plast Surg 30:327–332

    Article  PubMed  Google Scholar 

  5. Guigliano G, Nicoletti G, Grella E, Guigliano F, Esposito K, Scuderi N et al (2004) Effect of liposuction on insulin resistance and vascular inflammatory markers in obese woman. Br J Plast Surg 57:190–194

    Article  Google Scholar 

  6. Robles Cervantes JA, Yanez-Diaz S, Cordenas Camarena L (2004) Modification of insulin, glucose and cholesterol in nonobese woman undergoing liposuction. Is liposuction metabolically safe? Ann Plast Surg 52:64–67

    Article  PubMed  Google Scholar 

  7. Gonzales-Ortiz M, Robles-Cervantes JA, Cordenas Camarena L, Bustos-Saldana R, Martinez-Abundis E (2002) The effects of surgically removing subcutaneous fat on the metabolic profile and insulin sensitivity in obese women after large volume liposuction treatment. Horm Metab Res 34:446–449

    Article  Google Scholar 

  8. Rizzo MR, Paolisso G, Grella R, Barbieri M, Grella E et al (2005) Is dermolipectomy effective in improving insulin action and lowering inflammatory markers in obese woman? Clin Endocrinol 63:253–258

    Article  CAS  Google Scholar 

  9. Klein S, Fontana L, Young L, Coggan A, Kilo C, Patterson BW et al (2004) Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease. N Eng J Med 350:2549–2557

    Article  CAS  Google Scholar 

  10. Matthews DR, Hosker JP, Rudenski AS et al (1985) Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419

    Article  PubMed  CAS  Google Scholar 

  11. Blomqvist L, Eriksson A, Brandberg Y (2000) Reduction mammoplasty provides long term improvement in health status and quality of life. Plast Reconstr Surg 106(5):991–997

    Article  PubMed  CAS  Google Scholar 

  12. Chao JD, Memmel HC, Redding JF, Egan L, Odom LC, Casas LA (2002) Reduction mammoplasty is a functional operation, improving quality of life in symptomatic women: a prospective single center breast reduction outcome study. Plast Reconstr Surg 110(7):1644–1652

    Article  PubMed  Google Scholar 

  13. Jones SA, Bain JR (2001) Review of data describing outcomes that are used to assess changes in quality of life after reduction mammoplasty. Plast Reconstr Surg 108(1):62–67

    Article  PubMed  CAS  Google Scholar 

  14. Benditte-Klepetko H, Leisser V, Paternostro-Sluga T, Rakos M, Trattnig S, Helbich T, Schemper M, Deutinger M (2007) Hypertrophy of the breast: a problem of beauty or health? J Women Health (Larchmt) 16(7):1062–1069

    Article  Google Scholar 

  15. Gonzalez F, Walton RL, Shafer B, Matory WE Jr, Barah GL (1993) Reduction mammoplasty improves symptoms of macromastia. Plast Reconstr Surg 91:1270–1276

    Article  PubMed  CAS  Google Scholar 

  16. Mizgala CL, Mackenzie KM (2000) Breast reduction outcome study. Ann Plast Surg 44(2):125–133 discussion 133-134

    Article  PubMed  CAS  Google Scholar 

  17. Brown DM, Young VL (1993) Reduction mammoplasty for macromastia. Aesthetic Plast Surg 17:211–223

    Article  PubMed  CAS  Google Scholar 

  18. Pernia LR, Ronel DN, Leeper JD, Miller HL (2000) Carpal tunnel syndrome in women undergoing reduction mammoplasty. Plast Reconstr Surg 105:1314–1319

    Article  PubMed  CAS  Google Scholar 

  19. Rinomhota AS, Bulugahapitiya DUS, French SJ, Caddy CM, Griffiths RW et al (2008) Women gain weight and fat mass despite lipectomy at abdominoplasty and breast reduction. Eur J Endocrinol 158:349–352

    Article  PubMed  CAS  Google Scholar 

  20. Bailey JW, Anderson DB (1974) Rate of fat compensation and growth efficiency of lipectomized Sprague-Dawley rats. J Nutr 110:1785–1792

    Google Scholar 

  21. Chlouverakis C, Hojnicki D (1974) Lipectomy in obese hyperglycemic mice (ob/ob). Metabolism 23(2):133–137

    Article  PubMed  CAS  Google Scholar 

  22. Forger NG, Dark J, Zucker I (1986) Recovery of white adipose tissue after lipectomy in female ground squirrels. Can J Zool 64:128–131

    Article  Google Scholar 

  23. Hausman DB, Lu J, Ryan DH, Flatt WP, Harris Ruth BS (2004) Compensatory growth of adipose tissue after partial lipectomy: involvement of serum factors. Exp Biol Med 229:512–520

    CAS  Google Scholar 

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The authors declare that they have no conflicts of interest to disclose.

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Correspondence to Murat Sarıcı.

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Sarıcı, M., Erol Demirseren, M., Durgun, M. et al. Effects of Reduction Mammoplasty on Metabolic Profile and Body Weight. Aesth Plast Surg 35, 995–999 (2011). https://doi.org/10.1007/s00266-011-9719-7

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  • DOI: https://doi.org/10.1007/s00266-011-9719-7

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