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The EGF-TM7 family of the rat

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Abstract

EGF-TM7 receptors are adhesion class heptahelical molecules predominantly expressed by cells of the immune system. Based on an analysis of the recently unraveled genome, the EGF-TM7 family of the rat is described here. Like the mouse, the rat has three EGF-TM7 receptors—CD97, EMR1 and EMR4. The highest conservation between the orthologues lies within the membrane-spanning part and emphasizes the functional importance of this region.

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Acknowledgements

I like to thank Drs Sylvia Bähring, Erik Eldering and Robert Hoek for helpful suggestions . This study has been supported by the Royal Netherlands Academy of Arts and Sciences.

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Authors and Affiliations

  1. Laboratory for Experimental Immunology, G1-106, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE, Amsterdam, The Netherlands

    Jörg Hamann

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  1. Jörg Hamann
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Correspondence to Jörg Hamann.

Additional information

The nucleotide sequences reported here have been submitted to the GenBank database with the following accession numbers: AY686632 and AY686633.

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Hamann, J. The EGF-TM7 family of the rat. Immunogenetics 56, 679–681 (2004). https://doi.org/10.1007/s00251-004-0729-3

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  • DOI: https://doi.org/10.1007/s00251-004-0729-3

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