Summary
It is shown that Km of ChE is not affected by the neurohormones but Vmax is increased and decreased in presence of acceleratory and inhibitory neurohormones respectively. Hence it is suggested that the neurohormones might modulate the enzyme activity by altering the maximal velocities (Vmax) rather than affecting the enzyme affinity (Km) towards the substrate.
Similar content being viewed by others
References
S. A. T. Venkatachari and V. Devarajulu Naidu, Experientia25, 821 (1969).
S. A. T. Venkatachari and P. Murali Krishna Dass, Life Sci.7, 617 (1968).
K. P. Rao, Proc. 16th Int. Cong. Zool. Washington D. C. (1963).
K. P. Rao, J. Anim. Morph. Physiol.11, 133 (1964).
S. A. T. Venkatachari, Ind. J. exp. Biol.9, 338 (1971).
K. P. Rao, and T. Gopalakrishna Reddy, Nature, Lond.213, 1047 (1967).
S. A. T. Venkatachari, Marathwada Univ. J. Sci.13, 169 (1974).
B. Padmanabhanaidu, Nature, Lond.213, 410 (1967).
O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. Biol. Chem.193, 265 (1951).
T. E. Barman, in: Enzyme hand book. Springer-Verlag, New York 1970.
V. Devarajulu Naidu, S. A. T. Venkatachari and B. Padmanabhanaidu, Ind. J. exp. Biol.14, 550 (1976).
Author information
Authors and Affiliations
Additional information
Acknowledgment. The present study was carried out at S. V. University, Tirupati, A. P. India, and the authors are highly beholden to Prof. K. S. Swami, Head of the Department of Zoology, S. V. University, for his kind help and encouragement. Thanks are also due to the University Grants Commission, New Delhi, India, for placing one of them (N. V.) as a National Research Associate which made the present work possible.
Rights and permissions
About this article
Cite this article
Vasantha, N., Venkatachari, S.A.T., Mohan, P.M. et al. On the possible mode of action of neurohormones on cholinesterase activity in the ventral nerve cord of scorpion, Heterometrus fulvipes. Experientia 33, 238–239 (1977). https://doi.org/10.1007/BF02124087
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02124087