Abstract
Assessing the value of health care interventions is more and more a concern of governments, clinicians, health insurance companies, policy makers, and the general public. One dimension of the outcomes of such interventions that has received relatively little attention until recently is quality of life. However, during the last decade, measuring quality of life has become more frequent. Methodologies have also developed rapidly. At the same time, methodological problems continue to be troubling. In part, this explains the relative lack of use of validated measures of quality of life in clinical trials. In the future, measuring quality of life will certainly become more frequent. It may even be demanded by policy making bodies. Increasingly, too, economic costs will be part of such studies. This requires considering both clinical and economic data.
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References
Office of Technology Assessment. The implications of cost-effectiveness analysis of medical technology. Washington: US Government Printing Office, 1980.
Office of Technology Assessment. Strategies for medical technology assessment. Washington: US Government Printing Office, 1982.
Bergsma J, Engel G. Quality of life: does measurement help? Health Policy 1988; 10:267–79.
Bonsel G. Kwaliteit van leven meting en medical technology assessment [Quality of life measurement and medical technology assessment]. Ned Tijdschr Psychologie 1991;46:180–6.
O'Brien B, Buxton M, Ferguson B. Measuring the effectiveness of heart transplant programmes: quality of life data and their relationship to survival analysis. J Chron Dis 1987;40:137S-53S.
Pocock S. A perspective on the role of quality-of-life assessment in clinical trials. Controlled Clin Trials 1991;12:257S-65S.
Williams A. The importance of quality of life in policy decisions at three levels. J Drug Ther Res 1988;13:170–2.
Hunt S. Measuring health in clinical care and clinical trials. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:7–21.
Teeling Smith G. Introduction. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:1–5.
Feeny D, Labelle R, Torrance G. Integrating economic evaluations and quality of life assessments. In: Spilker B, ed. Quality of life assessments in clinical trials. New York: Raven Press, 1990.
Bossuyt PMM, Lubsen J. Introduction: assessing quality of life assessment. J Drug Ther Res 1988;13:151.
Patrick DL, Erickson P. What constitutes quality of life? Concepts and dimensions. J Drug Ther Res 1988;13:152–8.
Walker SR. Quality of life — principles and methodology. In: Van Eimeren W, Horisberger B, eds. Socioeconomic evaluation of drug therapy. Berlin: Springer-Verlag, 1988:151–65.
Erickson P, Patrick DL. Guidelines for selecting quality of life assessment: methodological and practical considerations. J Drug Ther Res 1988;13:159–63.
McEwen J. Nottingham Health Profile: application in clinical care. J Drug Ther Res 1988;13:164–6.
Sullivan M. The Sickness Impact Profile (SIP): an instrument for overall health assessment; a basic evaluation. J Drug Ther Res 1988;13:167–9.
Fries J. The hierarchy of quality-of-life assessment, the Health Assessment Questionnaire (HAQ) and issues mandating development of a toxicity index. Controlled Clin Trials 1991;12:106S-117S.
Essink Bot M, Rutten-Van Molken M. Het meten van gezondheid [The measurement of health]. Maastricht: Institute of Medical Technology Assessment, 1991. (IMTA Report MGZ 91-04).
Stevens J, Poston J, Walker S. Assessment of treatment of irritable bowel syndrome. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:211–23.
Hillner B, Smith T. Efficacy and cost effectiveness of adjuvant chemotherapy in women with node-negative breast cancer. N Engl J Med 1991;324:160–8.
Bennett K, Torrance G, Tugwell P. Methodological challenges in the development of utility measures of health-related quality of life in rheumatoid arthritis. Controlled Clin Trials 1991;12:118S-28S.
Patterson M. Assessment of treatment in rheumatoid arthritis. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:157–89.
Van Eimeren W, Horisberger B, eds. Socioeconomic evaluation of drug therapy. Berlin: Springer-Verlag, 1988.
Salek MS, Vandenburg MJ. Measuring the quality of life in angina pectoris. J Drug Ther Res 1988;13:186–91.
Fletcher AE, Bulpitt CJ. Assessment of quality of life in cardiovascular therapy. Br J Clin Pharm 1986;21:173S-81S.
Wenger N, Mattson M, Furburg C, Elinson J, eds. The assessment of quality of life in cardiovascular therapies. New York: Le Jacq Publishers, 1984.
Aaronson N, Beckman J, Bernheim J, Zittoun R, eds. The quality of life of cancer patients. New York: Raven Press, 1987.
Van Knippenberg F, Haes J. Measuring the quality of life of cancer patients: psychometric properties of instruments. J Clin Epidemiol 1988;41:1043–53.
Welburn P, Walker S. Assessment of quality of life in Parkinson's disease. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:89–108.
Lakke JPWF, Brouwer WH, Broersma TTW. Measuring the quality of life in neurological degenerative diseases. J Drug Ther Res 1988;13:176–80.
Morgan GJ. Quality of life assessment in rheumatoid arthritis: an overview. J Drug Ther Res 1988;13:192–4.
Wiklund I, Karlberg J. Evaluation of quality of life in clinical trials, selecting quality of life measures. Controlled Clin Trials 1991;12:204S-16S.
Spilker B, ed. Quality of life assessments in clinical trials. New York: Raven Press, 1990.
Guyatt G, Vandluyzen Van Zanten S, Feeny D, Patrick D. Measuring quality of life in clinical trials: a taxonomy and review. Can Med Assoc J 1989;140:1441–8.
Croog SH, Levine S, Testa MA, Brown B, Bulpitt CJ, Jankins D, et al. The effects of antihypertensive therapy on the quality of life. N Engl J Med 1986;314:1657–64.
Amery A, Fagard R, Staessen J, Van Hoof R. Measuring the quality of life in hypertension; a critical note. J Drug Ther Res 1988;13:184–5.
Bombardier C, Ware J, Russel IJ, Larson M, Chalmers A, Read JL. Auranofin therapy and quality of life in patients with rheumatoid arthritis: results of a clinical trial. JAMA 1986;81:565–78.
Jones PW. Quality of life measurement in chronic lung disease. J Drug Ther Res 1988;13:181–3.
Schipper H, Clinch J. Assessment of treatment in cancer. In: Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988:109–55.
Schipper H, Clinch J, McMurray A, Levitt M. Measuring the quality of life of cancer patients: the Functional Living Index — Cancer. J Clin Oncol 1984;2:472–83.
Van Dam FSAM, Aaronson NK. Quality of life and cancer treatment. J Drug Ther Res 1988;13:173–5.
Office of Technology Assessment. A review of selected vaccine and immunization policies. Washington: US Government Printing Office, 1979.
Haan G, Van Doorslaer E. Onderzoek naar kosten-effectiviteit van geneesmiddelen [Research on the cost-effectiveness of pharmaceutical treatments]. Pharm Weekbl 1991;126:254–62.
Dao TD. Cost-benefit and cost-effectiveness of pharmaceutical intervention. Washington: Pharmaceutical Manufacturing Association, 1984.
Luce BR. Cost-effectiveness study of Pharmaceuticals: methodological considerations. In: Van Eimeren W, Horisberger B, eds. Socioeconomic evaluation of drug therapy. Berlin: Springer-Verlag, 1988:87–94.
Teeling Smith G, ed. Measuring health: a practical approach. New York: John Wiley & Sons, 1988.
Drummond MF, Stoddart GL, Torrance GW. Methods for the economic evaluation of health care programmes. Oxford: Oxford Medical Publications, 1987.
Weeks J, Tierney M. Weinstein M. Cost-effectiveness of prophylactic intravenous immune globulin in chronic lymphocytic leukemia. N Engl J Med 1991;325:81–6.
Evans R, Rader B, Mannenen D, Cooperative Multicenter EPO Clinical Trial Group. The quality of life of hemodialysis recipients treated with recombinant human erythropoietin. JAMA 1990;263:825–30.
Laupacis A, Wong C, Churchill D, Canadian Erythropoetin Group. The use of generic and specific quality-of-life measures in hemodialysis patients treatment with erythropoietin. Controlled Clin Trials 1991;12:168S-79S.
Doolittle R. Biotechnology — the enormous cost of success. [Editorial]. N Engl J Med 1991;324:1360–2.
Canadian Erythropoietin Study Group. Association between recombinant human erythropoietin and quality of life and exercise capacity of patients receiving haemodialysis. BMJ 1990;300:573–5.
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Banta, H.D. Quality of life 1. Pharm World Sci 15, 45–49 (1993). https://doi.org/10.1007/BF01874082
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DOI: https://doi.org/10.1007/BF01874082