Abstract
Both the neurohormonal theory of sexual orientation and previous research on humans and animals suggest that male homosexuality may arise from prenatal stress during the brain's sexual differentiation. Stress-proneness and retrospective reports of stress during pregnancy were obtained from mothers of male and female heterosexuals, bisexuals, and homosexuals. Each mother also rated pregnancy stress for a heterosexual sibling of the subject. For males, neither between-family nor within-family analyses revealed a maternal stress effect for either sexual orientation or childhood gender nonconformity. However, mothers of effeminate children reported more stress-proneness than other mothers. Male homosexuality nevertheless was strongly familial, suggesting a reconsideration of genetic and familial environmental mechanisms.
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References
Adkins-Regan, E. (1988). Sex hormones and sexual orientation in animals.Psychobiology 16: 335–347.
Anderson, R. H., Fleming, D. E., Rhees, R. W., and Kinghorn, E. (1986). Relationships between sexual activity, plasma testosterone, and the volume of the sexual dimorphic nucleus of the preoptic area in prenatally stressed and non-stressed rats.Brain Res. 370: 1–10.
Baum, M. J. (1976). Effects of testosterone propionate administered perinatally on sexual behavior of female ferrets.J. Comp. Physiol. Psychol. 90: 399–410.
Bell, A. P., Weinberg, M. S., and Hammersmith, S. K. (1981).Sexual Preference: Its Development in Men and Women Indiana University Press, Bloomington.
Buss, A. H., and Plomin, R. (1984).Temperament: Early Developing Personality Traits Erlbaum, Hillsdale, NJ.
Conley, J. J. (1984). The hierarchy of consistency: A review and model of longitudinal findings on adult individual differences in intelligence, personality, and self-opinion.Pers. Indiv. Diff. 5: 11–25.
Dörner, G., and Hinz, G. (1968). Induction and prevention of male homosexuality by androgens.J. Endocrinol. 40: 387–388.
Dörner, G., Geiser, T., Ahrens, L., Krell, L., Munz, G., Sieler, H., Kittner, E., and Muller, H. (1980). Prenatal stress and possible aetiogenetic factor homosexuality in human males.Endokrinologie 75; 365–368.
Dörner, G., Schenk, B., Schmiedel, B., and Ahrens, L. (1983). Stressful events in prenatal life of bi- and homosexual men.Exp. Clin. Endocrinol. 81: 83–87.
Dohrenwend, B. S., Krasnoff, L., Askenasy, A. R., and Dohrenwend, B. P. (1978). Exemplification of a method for scaling life events: the PERI life events scale.J. Health Soc. Behav. 19: 205–229.
Eckert, E. D., Bouchard, T. J., Bohlen, J., and Heston, L. L. (1986). Homosexuality in monozygotic twins reared apart.Br. J. Psychiat. 148: 421–425.
Ellis, L., and Ames, M. A. (1987). Neurohormonal functioning and sexual orientation: A theory of homosexuality-heterosexuality.Psychol. Bull. 101: 233–258.
Ellis, L., Ames, M. A., Peckham, W., and Burke, D. (1988). Sexual orientation of human offspring may be altered by severe maternal stress during pregnancy.J. Sex Res. 25: 152–157.
Funk, S. C., and Houston, B. K. (1987). A critical analysis of the hardiness scale's validity and utility.J. Pers. Soc. Psychol. 53: 572–578.
Gladue, B. A., Green, R., and Hellman, R. E. (1984) Neuroendocrine response to estrogen and sexual orientation.Science 225: 1469–1499.
Gooren, L. (1986). The neuroendocrine response of luteinizing hormone to estrogen administration in heterosexual, homosexual, and transsexual subjects.J. Clin. Endocrinol. Metab. 63: 583–588.
Gottesman, I. I., and Carey, G. (1983). Extracting meaning and direction from twin data.Psychiat. Dev. 1: 35–50.
Green, R. (1987).The “Sissy Boy Syndrome” and the Development of Homosexuality Yale University Press, New Haven.
Harry, J. (1983). Defeminization and adult psychological well-being among male homosexuals.Arch. Sex. Behav. 12: 1–19.
Hendricks, S. E., Graber, B., and Rodriguez-Sierra, J. F. (1989). Neuroendocrine responses to exogenous estrogen: No differences between heterosexual and homosexual men.Psychoneuroendocrinology 14: 177–185.
Herrenkohl, L. R., and Politch, J. A. (1978). Effects of prenatal stress on the estrous cycle of female offspring as adults.Experientia 34: 1240–1241.
Katz, J. L., Ackman, P., Rothwax, Y., Sachar, E. J., Weiner, H., Hellman, L., and Gallagher, T. F. (1970). Psychoendocrine aspects of cancer of the breast.Psychosom. Med. 32: 1–18.
Kinsey, A. C., Pomeroy, W. B., and Martin, C. E. (1948).Sexual Behavior in the Human Male Saunders, Philadelphia.
Kobasa, S. C. (1979). Stressful life events, personality, and health: An inquiry into hardiness.J. Pers. Soc. Psychol. 37: 1–11.
Kobasa, S. C., and Puccetti, M. (1983). Personality and social resources in stress-resistance.J. Pers. Soc. Psychol. 45: 839–850.
Kobasa, S. C., Maddi, S. R., and Kahn, S. (1982). Hardiness and health: A prospective study.J. Pers. Soc. Psychol. 42: 168–177.
Money, J. (1987). Sin, sickness or status? Homosexual gender identity and psychoneuroendocrinology.Am. Psychol. 42: 384–399.
Money, J., Schwartz, M., and Lewis, V. G. (1984). Adult erotosexual status and fetalhormonal masculinization and demasculinization: 46, XX congenital virilizing adrenal hyperplasia and 46, XY androgen-insensitivity syndrome compared.Psychoneuroendocrinology 9: 405–414.
Moore, C. L. (1989). Crowding during pregnancy and sexual behavior of male progeny in Long-Evans rats: No effects on lordosis, masculine copulatory behavior, reproductive success, or rate of decline after castration.Conference on Reproductive Behavior, Saratoga Springs, New York. (Abstract)
Phoenix, C. H. (1974). Prenatal testosterone in nonhuman primate and its consequences for behavior. In Friedman, R. C., Richart, R. M., and Vande Wiele, R. L. (eds.),Sex Differences in Behavior pp. 19–31, Wiley, New York.
Pillard, R. C., and Weinrich, J. D. (1986). Evidence of familial nature of male homosexuality.Arch. Gen. Psychiat. 43: 808–812.
Plomin, R., DeFries, J. C., and McClearn, G. E. (1989).Behavioral Genetics: A Primer W. H. Freeman, New York.
Politch, J. A., and Herrenkohl, L. R. (1984). Effects of prenatal stress on reproduction in male and female mice.Physiol. Behav. 32: 95–99.
Reich, T., Cloninger, C. R., and Guze, S. B. (1975). The multifactorial model of disease transmission: I. Description of the model and its use in psychiatry.Br. J. Psychiat. 127: 1–10.
Rosenthal, D. (1971).Genetics of Psychopathology McGraw-Hill, New York.
Ruse, M. (1988).Homosexuality Blackwell, Oxford.
Sachar, E. J. (1980). Hormonal changes in stress and mental illness. In Krieger, D. T., and Hughes, J. C. (eds.), Neuroendocrinology, pp. 177–183, H. P. Publishing, New York.
Schmidt, G., and Clement, U. (1988). Does peace prevent homosexuality? International Academy of Sex Research, Minneapolis, Minnesota. (Abstract)
Ward, I. L. (1972). Prenatal stress feminizes and demasculizes the behavior of males.Science 175: 82–84.
Ward, I. L. (1984). The prenatal stress syndrome: Current status.Psychoneuroendocrinology 9: 3–11.
Ward, I. L., and Renz, F. J. (1972). Consequences of perinatal hormone manipulation on the adult sexual behavior of female rats.J. Comp. Physiol. Psychol. 78: 349–355.
Ward, I. L., and Weisz, J. (1980). Maternal stress alters plasma testosterone in fetal males.Science 207: 328–329.
Weinrich, J. D. (1987).Sexual Landscapes Scribner's, New York.
Whitam, F. (1977). Childhood indicators of male homosexuality.Arch. Sex. Behav. 6: 89–96.
Wille, R., Borchers, D., and Schultz, W. (1987). Prenatal distress—A disposition for homosexuality.International Academy of Sex Research, Tutzing, FRG. (Abstract)
Wilson, E. O. (1978).On Human Nature Harvard University Press, Cambridge, MA.
Winer, B. J. (1971).Statistical Principles in Experimental Design McGraw-Hill, New York.
Wolff, C. T. Friedman, S. B., Hofer, M. A., and Mason, J. W. (1964). Relationship between psychological defenses and mean urinary 17-hydrocorticosteroid excretion rates.Psychosom. Med. 26: 576–591.
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Bailey, J.M., Willerman, L. & Parks, C. A test of the maternal stress theory of human male homosexuality. Arch Sex Behav 20, 277–293 (1991). https://doi.org/10.1007/BF01541847
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DOI: https://doi.org/10.1007/BF01541847