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The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium

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Summary

Vascular glioblastomas become liquefied when contaminated with spores of the non-pathogenic Clostridium butyricum M 55. The spores are administered by intracarotid injection. The oncolysis is complete one week after injection. The glioblastoma is converted into a brain abscess which is then operated on appropriately. Forty nine patients have been treated in this manner. The rate of recurrence, however, remained uninfluenced.

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References

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Author notes

  1. F. Heppner

    Present address: Neurosurgical Department, University of Graz, Graz, Austria

Authors and Affiliations

  1. Neurosurgical Department, University of Graz, Graz, Austria

    J. R. Möse

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  1. F. Heppner
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  2. J. R. Möse
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Heppner, F., Möse, J.R. The liquefaction (oncolysis) of malignant gliomas by a non pathogenic Clostridium. Acta neurochir 42, 123–125 (1978). https://doi.org/10.1007/BF01406639

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  • DOI: https://doi.org/10.1007/BF01406639

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