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short-latency somatosensory evoked potentials to median nerve stimulation: components N 13-P 13, N 14-P 14, P 15, P 16 and P 18 with different recording methods

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Summary

Comparative recordings of short-latency somatosensory evoked potentials with midfrontal (Fz), ear and non-cephalic reference electrodes were obtained in 12 normal subjects to define the site of the generators of the different components and the spatial distribution and interference of the different components recorded at the neck and scalp. Such investigations provide the basis for identical investigations in patients with focal lesions of the central nervous system. The N 13 recorded from the neck (C 2-Fz) and the inconsistently recorded component N 14 were quite similar in latency to the far-field potentials P 13 and P 14 recorded at the scalp (C3′, C4′—ear or hand). The component P 15 was clearly visible only in scalp-Fz leads and occurred 0.2–0.9 ms (mean 0.5 ms) later than P 14 in ear or hand reference recordings. This is evidence against the identity of these two components proposed by others. In a larger group of 48 subjects, using an exclusive Fz-reference lead, normal values were established of the components P 15, P 16 and P 18, as well as their scalp distribution.

Zusammenfassung

An 48 Normalpersonen wurden die Normalwerte der spinalen und subkortikalen SEP-Komponenten (einschließlich P 16 und P 18) nach Medianus-Stimulation am Handgelenk ermittelt, wobei eine frontomediane Referenz (Fz) gewählt wurde. Bei einem Teil der Probanden (n=12) erfolgten zusätzliche Ableitungen der Reizantworten gegen eine Ohr- sowie eine extrakephale (Hand-) Referenz, um die Beziehungen der hierbei registrierbaren positiven „Far-field-Potentiale“ zu den einzelnen Komponenten des Nacken-SEP zu klären. Die von der oberen Nackenpartie (C 2-Fz) abgeleiteten Komponenten N 13 und N 14 stimmten in ihrer Latenz mit den von der Kopfhaut abgeleiteten Komponenten P 13 und P 14 überein, wobei ein Teil der Probanden anstelle zweier deutlich unterscheidbarer P 13- und P 14-Komponenten lediglich eine positive Potentialschwankung aufwies. Die bei frontomedianer Referenz konstant sichtbare P 15-Komponente wies bei allen Untersuchten eine 0,2–0,9 ms längere Latenz auf als das mit extrakephaler Referenz registrierte Far-field-Potential P 14, was gegen die von anderer Seite vermutete Identität dieser beiden Komponenten spricht. Die klare gegenseitige Abgrenzung der frühen somatosensiblen Reizantworten nach Medianusstimulation bei Wahl unterschiedlicher Referenzorte ist Voraussetzung für eine verfeinerte Lokalisationsdiagnostik innerhalb des lemniskalen Systems der Somatosensorik.

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Stöhr, M., Riffel, B. short-latency somatosensory evoked potentials to median nerve stimulation: components N 13-P 13, N 14-P 14, P 15, P 16 and P 18 with different recording methods. J Neurol 228, 39–47 (1982). https://doi.org/10.1007/BF00313408

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