Skip to main content
SpringerLink
Log in

Synthesis and structural peculiarities of gallium Complexes with novel paullone derivatives

  • Published:
Central European Journal of Chemistry

Abstract

9-Bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6-ylhydrazine was reacted with 2-acetylpyridine to give a Schiff base as a potential tridentate ligand. The reaction of this ligand with gallium chloride afforded complexes of 1:1 and 2:1 stoichiometry. The results of X-ray diffraction studies of the ligand and both gallium complexes are reported and compared with the data for a related gallium complex with a Schiff base obtained from 9-bromo-7,12-dihydroindolo[3,2-d][1]benzazepin-6-ylhydrazine and 2-hydroxybenzaldehyde.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. D.W. Zaharevitz, R. Gussio, M. Leost, A.M. Senderowicz, T. Lahusen, C. Kunick, L. Meijer, E.A. Sausville, Cancer Res. 59, 2566 (1999).

    CAS  PubMed  Google Scholar 

  2. E.B. Skibo, X. Huang, R. Martinez, R.H. Lemus, W.A. Craigo, J. Med. Chem. 55, 5543 (2002).

    Article  Google Scholar 

  3. C. Schultz, A. Link, M. Leost, D.W. Zaharevitz, R. Gussio, E.A. Sausville, L. Meijer, Kunick, J. Med. Chem. 42, 2909 (1999).

    Article  CAS  Google Scholar 

  4. J. Trapp, A. Jochum, R. Meier, L. Saunders, B. Marshall C. Kunick, E. Verdin, P. Goekjian, W. Sippl, M. Jung, J. Med. Chem. 49, 7307 (2006)

    Article  CAS  Google Scholar 

  5. W.F. Schmid, S. Zorbas-Seifried, R.O. John, V.B. Arion, M.A. Jakupec, A. Roller, M.S. Galanski, I. Chiorescu, H. Zorbas, B.K. Keppler, Inorg. Chem. 46, 3645 (2007).

    Article  CAS  Google Scholar 

  6. W.F. Schmid, R.O. John, G. Muehlgassner, P. Heffeter, M.A. Jakupec, M.S. Galanski, W. Berger, V.B. Arion, B.K. Keppler, J. Med. Chem. 50, 6343 (2007).

    Article  CAS  Google Scholar 

  7. A. Dobrov, V.B. Arion, N. Kandler, W. Ginzinger, M.A. Jakupec, A. Rufinska, N. Graf von Keyserlingk, M.S. Galanski, C. Kowol, B.K. Keppler, Inorg. Chem. 45, 1945 (2006).

    Article  CAS  Google Scholar 

  8. Z. Otwinowski, W. Minor, In: C.W. Carter Jr., R.M. Sweet, (Eds.), Methods in Enzymology Vol. 276: Macromolecular Crystallography Part A (Academic Press, London, 1997), 307

    Chapter  Google Scholar 

  9. G.M. Sheldrick, SHELXS-97, Program for Crystal Structure Solution, University of Goettingen, Goettingen (1997)

    Google Scholar 

  10. Sheldrick G. M., SHELXL-97, Program for Crystal Structure Refinement, University of Goettingen, Goettingen (1997)

    Google Scholar 

  11. A.J.C. Wilson (Ed.), International Tables for X-ray Crystallography Vol. C (Kluwer Academic Publishers, Dordrecht, 1992), Tables 4.2.6.8 and 6.1.1.4

    Google Scholar 

  12. A.L. Spek, J. Appl. Cryst. 36, 7 (2003).

    Article  CAS  Google Scholar 

  13. Bruker, XP (Version 5.1), Bruker AXS Inc., Madison, Wisconsin, USA (1998)

  14. A.W. Addison, T.N. Rao, J. Reedijk, J. van Rijn, G.C. Verschoor, J. Chem. Soc. Dalton Trans. 7, 1349 (1984).

    Article  Google Scholar 

  15. K. Robinson, G.V. Gibbs, P.H. Ribbe, Science 172, 567 (1971).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Inorganic Chemistry, University of Vienna, A-1090, Vienna, Austria

    Werner Ginzinger, Vladimir B. Arion, Mathea Sophia Galanski & Bernhard K. Keppler

  2. Institute of Mineralogy and Crystallography, University of Vienna, A-1090, Vienna, Austria

    Gerald Giester

Authors
  1. Werner Ginzinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Vladimir B. Arion
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gerald Giester
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Mathea Sophia Galanski
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Bernhard K. Keppler
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Vladimir B. Arion.

About this article

Cite this article

Ginzinger, W., Arion, V.B., Giester, G. et al. Synthesis and structural peculiarities of gallium Complexes with novel paullone derivatives. cent.eur.j.chem. 6, 340–346 (2008). https://doi.org/10.2478/s11532-008-0048-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.2478/s11532-008-0048-x

Keywords

Search

Navigation