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Fertility outcomes in infertile women with complex hyperplasia or complex atypical hyperplasia who received progestin therapy and in vitro fertilization

子宫内膜不典型增生或复杂性增生不孕患者孕激 素和IVF后的妊娠结局分析

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概 要

本回顾性队列研究包括了年龄在45岁以下被诊断为伴有或不伴有不典型增生的子宫内膜复杂性增生患者, 对孕激素治疗后的临床结局及妊娠结局进行了比较。结果表明, 伴有或不伴有不典型增生的子宫内膜复杂性增生接受孕激素治疗后, 其临床及妊娠结局并没有显著差异。 我们认为对于这些患者, 在短暂的孕激素治疗控制病情后, 尽快施行体外受精—胚胎移植治疗 (IVF) 将有利于改善其妊娠结局。

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Acknowledgements

We thank BioMed Proofreading LLC for revising the manuscript. We thank Prof. Zi-jiang CHEN of Shandong University (Jinan, China) for her kind guidance of the study.

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  1. The two authors contributed equally to this work

Authors and Affiliations

  1. Center for Reproductive Medicine, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250012, China

    Miao Li, Jia-lun Song, Ying Zhao, She-ling Wu, Hong-bin Liu, Rong Tang & Lei Yan

  2. National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, 250012, China

    Miao Li, Jia-lun Song, She-ling Wu, Hong-bin Liu, Rong Tang & Lei Yan

  3. The Key Laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, 250012, China

    Miao Li, Jia-lun Song, She-ling Wu, Hong-bin Liu, Rong Tang & Lei Yan

Authors
  1. Miao Li
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  2. Jia-lun Song
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  3. Ying Zhao
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  4. She-ling Wu
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Corresponding author

Correspondence to Lei Yan.

Additional information

Project supported by the National Natural Science Foundation of China (No. 81571414), the key Research and Development Program of Shandong Province (No. 2015gsf118124), and the Chinese Medical Association of Clinical Medicine Research Special Funds (No. 16020290645), China

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Li, M., Song, Jl., Zhao, Y. et al. Fertility outcomes in infertile women with complex hyperplasia or complex atypical hyperplasia who received progestin therapy and in vitro fertilization. J. Zhejiang Univ. Sci. B 18, 1022–1025 (2017). https://doi.org/10.1631/jzus.B1600523

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  • DOI: https://doi.org/10.1631/jzus.B1600523

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