Conclusion
The eggshell represents an important case of rapid, highly structured, and regulated biomineralization. Analysis of the composition, microstructure, and crystallography of the avian eggshell by a variety of analytical methods have resulted in a surprisingly varied, often confusing and inconsistent picture of eggshell structure and function, which has been presented here in only the briefest outline. Assembly of the eggshell takes place in a sequential process involving three or more distinct secretory tissues and five-ten (or more) specific biopolymers that appear to regulate either eggshell physical properties or the crystal formation/resorption processes. Investigation of the individual chemical components of the eggshell system, and the mechanisms by which the process of eggshell assembly is controlled, should lead to new insights into the general principles of biomineralization, and new approaches for fabricating nonbiological composite ceramic structures.
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References
A.L. Romanoff and A.J. Romanoff, The Avian Egg (Wiley and Sons, New York, 1949).
C. Tyler, Wilhelm von Nathusius. On Avian Eggshells. A Translated and Edited Version of His Work (University of Reading, Reading, England, 1964).
S.E. Solomon, in Physiology and Biochemistry of the Domestic Fowl, Vol. 4, edited by B.M. Freeman (Academic Press, New York, 1983) p. 379–419.
D.S. Robinson and N.R. King, Nature 199 (1963) p. 497–498.
J.W. Dieckert, M.C. Dieckert, and C.R. Creger, Poultry Science 68 (1989) p. 1569–1584.
M. Wong, M.J.C. Hendrix, K. von der Mark, C. Little, and R. Stern, Developmental Biology 104 (1984) p. 28–36.
J.L. Arias, M.S. Fernandez, J.E. Dennis, and A.I. Caplan, Matrix 11 (1991) p. 313–320; Connective Tissue Res. 26 (1991) p. 37–45.
T.M. Wu, J. Arias, D.J. Fink, A.I. Caplan, and A.H. Heuer, to be published.
J.P. Rodriguez, J. Arias, T.M. Wu, M. Agarwal, S.-Q. Xiao, D.J. Fink, A.I. Caplan, and A.H. Heuer, to be published.
C. Quintana and D. Sandoz, Calcified Tissue Res. 25 (1978) p. 145–159.
S.-Q. Xiao, S. Baden, and A.H. Heuer, to be published.
H. Silyn-Roberts and R.M. Sharp, Proc. R. Soc. Lond. B227 (1986) p. 303–324.
B.R. Long and T.R. Wilshaw, Fracture of Brittle Solids (Cambridge University Press, Cambridge, 1975) p. 100.
A.R. Terepka, Exper. Cell Res. 30 (1963) p. 1117–1182; 30 (1963) p. 183–192.
T.-M. Wu, D.J. Fink, J.L. Arias, J.P. Rodriguez, A.H. Heuer, and A.I. Caplan, in Chemistry and Biology of Mineralized Tissues, edited by H.C. Slavkin and P. Price (Elsevier, New York, in press).
S. Schwartz, B.D. Stephenson, D.H. Sarkar, and R. Bracko, Ann. N. Y. Acad. Sci. 244 (1975) p. 570–590.
G.Y. Kennedy and H.G. Vevers, Comp. Biochem. Physiol. 55B (1976) p. 117–123.
E. Salevsky Jr. and R.M. Leach Jr., Poultry Sci. 59 (1980) p. 438–443.
C.R. Creger, H. Phillips, and J.T. Scott, Poultry Sci. 55 (1976) p. 1717–1723.
B.H. Stemberger, W.J. Mueller, and R.M. Leach, Jr., Poultry Sci. 56 (1977) p. 537–543.
Y. Nys, J. Rawadzki, J. Gautron, and A.D. Mills, Poultry Sci. 70 (1991) p. 1236–1245.
R.G. Board, Biol. Rev. 57 (1982) p. 1–28.
A.H. Heuer, D.J. Fink, V.J. Laraia et al., Science 255 (1992) p. 1098–1105.
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Fink, D.J., Caplan, A.I. & Heuer, A.H. Eggshell Mineralization: A Case Study of a Bioprocessing Strategy. MRS Bulletin 17, 27–31 (1992). https://doi.org/10.1557/S0883769400046443
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DOI: https://doi.org/10.1557/S0883769400046443