Skip to main content
Log in

Eggshell Mineralization: A Case Study of a Bioprocessing Strategy

  • Biology and Materials Synthesis
  • Nature’s Way…Biomineralization
  • Published:
MRS Bulletin Aims and scope Submit manuscript

Conclusion

The eggshell represents an important case of rapid, highly structured, and regulated biomineralization. Analysis of the composition, microstructure, and crystallography of the avian eggshell by a variety of analytical methods have resulted in a surprisingly varied, often confusing and inconsistent picture of eggshell structure and function, which has been presented here in only the briefest outline. Assembly of the eggshell takes place in a sequential process involving three or more distinct secretory tissues and five-ten (or more) specific biopolymers that appear to regulate either eggshell physical properties or the crystal formation/resorption processes. Investigation of the individual chemical components of the eggshell system, and the mechanisms by which the process of eggshell assembly is controlled, should lead to new insights into the general principles of biomineralization, and new approaches for fabricating nonbiological composite ceramic structures.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A.L. Romanoff and A.J. Romanoff, The Avian Egg (Wiley and Sons, New York, 1949).

    Google Scholar 

  2. C. Tyler, Wilhelm von Nathusius. On Avian Eggshells. A Translated and Edited Version of His Work (University of Reading, Reading, England, 1964).

    Google Scholar 

  3. S.E. Solomon, in Physiology and Biochemistry of the Domestic Fowl, Vol. 4, edited by B.M. Freeman (Academic Press, New York, 1983) p. 379–419.

    Google Scholar 

  4. D.S. Robinson and N.R. King, Nature 199 (1963) p. 497–498.

    Article  CAS  Google Scholar 

  5. J.W. Dieckert, M.C. Dieckert, and C.R. Creger, Poultry Science 68 (1989) p. 1569–1584.

    Article  CAS  Google Scholar 

  6. M. Wong, M.J.C. Hendrix, K. von der Mark, C. Little, and R. Stern, Developmental Biology 104 (1984) p. 28–36.

    Article  CAS  Google Scholar 

  7. J.L. Arias, M.S. Fernandez, J.E. Dennis, and A.I. Caplan, Matrix 11 (1991) p. 313–320; Connective Tissue Res. 26 (1991) p. 37–45.

    Article  CAS  Google Scholar 

  8. T.M. Wu, J. Arias, D.J. Fink, A.I. Caplan, and A.H. Heuer, to be published.

  9. J.P. Rodriguez, J. Arias, T.M. Wu, M. Agarwal, S.-Q. Xiao, D.J. Fink, A.I. Caplan, and A.H. Heuer, to be published.

  10. C. Quintana and D. Sandoz, Calcified Tissue Res. 25 (1978) p. 145–159.

    Article  CAS  Google Scholar 

  11. S.-Q. Xiao, S. Baden, and A.H. Heuer, to be published.

  12. H. Silyn-Roberts and R.M. Sharp, Proc. R. Soc. Lond. B227 (1986) p. 303–324.

    Google Scholar 

  13. B.R. Long and T.R. Wilshaw, Fracture of Brittle Solids (Cambridge University Press, Cambridge, 1975) p. 100.

    Google Scholar 

  14. A.R. Terepka, Exper. Cell Res. 30 (1963) p. 1117–1182; 30 (1963) p. 183–192.

    Google Scholar 

  15. T.-M. Wu, D.J. Fink, J.L. Arias, J.P. Rodriguez, A.H. Heuer, and A.I. Caplan, in Chemistry and Biology of Mineralized Tissues, edited by H.C. Slavkin and P. Price (Elsevier, New York, in press).

  16. S. Schwartz, B.D. Stephenson, D.H. Sarkar, and R. Bracko, Ann. N. Y. Acad. Sci. 244 (1975) p. 570–590.

    Article  CAS  Google Scholar 

  17. G.Y. Kennedy and H.G. Vevers, Comp. Biochem. Physiol. 55B (1976) p. 117–123.

    Google Scholar 

  18. E. Salevsky Jr. and R.M. Leach Jr., Poultry Sci. 59 (1980) p. 438–443.

    Article  CAS  Google Scholar 

  19. C.R. Creger, H. Phillips, and J.T. Scott, Poultry Sci. 55 (1976) p. 1717–1723.

    Article  Google Scholar 

  20. B.H. Stemberger, W.J. Mueller, and R.M. Leach, Jr., Poultry Sci. 56 (1977) p. 537–543.

    Article  Google Scholar 

  21. Y. Nys, J. Rawadzki, J. Gautron, and A.D. Mills, Poultry Sci. 70 (1991) p. 1236–1245.

    Article  CAS  Google Scholar 

  22. R.G. Board, Biol. Rev. 57 (1982) p. 1–28.

    Article  Google Scholar 

  23. A.H. Heuer, D.J. Fink, V.J. Laraia et al., Science 255 (1992) p. 1098–1105.

    Article  CAS  Google Scholar 

Download references

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fink, D.J., Caplan, A.I. & Heuer, A.H. Eggshell Mineralization: A Case Study of a Bioprocessing Strategy. MRS Bulletin 17, 27–31 (1992). https://doi.org/10.1557/S0883769400046443

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1557/S0883769400046443

Navigation