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Genotyping of Plasmodium spp.

Nested PCR

  • Protocol
Malaria Methods and Protocols

Part of the book series: Methods in Molecular Medicine™ ((MIMM,volume 72))

Abstract

It is now established that Plasmodium falciparum parasites found in any one area are highly diverse and that individual hosts, vertebrate and insect, are often concurrently infected by multiple parasite lines (for example, see refs. 1-4). Different parasite lines of the same Plasmodium species are also known to vary substantially with respect to parameters such as the parasitological and clinical course of the infection, the pattern of recrudescence, immunological cross-reactivity, susceptibility to drugs, and transmissibility by various vector species. The relationship between the complexity of the parasite populations and such pathological, immunological, and epidemiological factors is poorly understood and clearly merits further investigation (for example, see refs. 4-16).

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Author information

Authors and Affiliations

  1. Bio-medical Parasitology, Institut Pasteur, Paris, France

    Georges Snounou

Authors
  1. Georges Snounou
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Editor information

Editors and Affiliations

  1. Malaria Program, Naval Medical Research Center, Silver Spring, MD, USA

    Denise L. Doolan

  2. Department of Molecular Microbiology and Immunology, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD, USA

    Denise L. Doolan

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© 2002 Humana Press Inc.

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Snounou, G. (2002). Genotyping of Plasmodium spp.. In: Doolan, D.L. (eds) Malaria Methods and Protocols. Methods in Molecular Medicine™, vol 72. Humana Press. https://doi.org/10.1385/1-59259-271-6:103

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  • DOI: https://doi.org/10.1385/1-59259-271-6:103

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-823-3

  • Online ISBN: 978-1-59259-271-5

  • eBook Packages: Springer Protocols

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