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Synthesis and characterization of novel bis-triazolyl quinazolinones

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Abstract

A series of 2-methyl-1-[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl]-2-(4-{[(1-phenyl-1H-1,2,3-triazol-4-yl)methyl}amino]phenyl)-2,3-dihydroquinazolin-4(1H)-ones have been synthesized by click chemistry from 2-methyl-1-(prop-2-yn-1-yl)-2-[4-(prop-2-yn-1-ylamino)phenyl]-2,3-dihydroquinazolin-4(1H)-one and substituted azides. The newly synthesized quinazolinones have been characterized by 1H and 13C NMR, IR, and mass spectral data and elemental analyses.

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Authors and Affiliations

  1. Department of Chemistry, University College of Technology, Osmania University, Hyderabad, 500007, India

    N. J. P. Subhashini & G. Swetha

  2. Department of Chemistry, University College of Science, Osmania University, Hyderabad, 500007, India

    Shivaraj

Authors
  1. N. J. P. Subhashini
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  2. G. Swetha
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  3. Shivaraj
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Correspondence to N. J. P. Subhashini.

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Subhashini, N.J.P., Swetha, G. & Shivaraj Synthesis and characterization of novel bis-triazolyl quinazolinones. Russ J Gen Chem 87, 1813–1819 (2017). https://doi.org/10.1134/S107036321708028X

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