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Frontonasal Malformation Diagnosis in the First Trimester: A Case Report

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Journal of Fetal Medicine

Abstract

Different components of the face and the brain develop independently and ultimately unite at the midline. Disruptions in the development and fusion of craniofacial midline give rise to myriad of abnormalities broadly classified as frontonasal malformations. Here, we report a case diagnosed in the first trimester. The fetus had midline cleft of the face extending till forehead, cleft lip and palate, absent nasal tip and arhinia. There was associated alobar holoprosencephaly and polydactyly in all the four limbs. This case illustrates the importance of evaluation of facial profile, retronasal triangle and 3 D scanning at the time of first trimester screening.

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Authors and Affiliations

  1. Fetal Medicine Department, Kailash Hospital, C-601, Amrapali Platinum Apartments, Sector 119, Noida, 201305, India

    Neha Gupta

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  1. Neha Gupta
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Correspondence to Neha Gupta.

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Gupta, N. Frontonasal Malformation Diagnosis in the First Trimester: A Case Report. J. Fetal Med. 6, 201–204 (2019). https://doi.org/10.1007/s40556-019-00221-x

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  • DOI: https://doi.org/10.1007/s40556-019-00221-x

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