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Placento-Cranial Adhesion: A New Syndromic Association

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Journal of Fetal Medicine

Abstract

Cases of placento-cranial adhesion are rare and most of them are incompatible with life. A few case reports in the literature have included such cases under the overarching rubric of amniotic band syndrome. We present autopsy findings of four cases with gestation period ranging from 16 to 21 weeks. All of them displayed placenta-cranial adhesion, low weight for gestation, absence of flat bones of skull, anencephaly, dysmorphic facial features, short umbilical cord and limb/digit amputation with oligohydrambios. Three out of four showed nasal groove. We propose that there are grounds for syndromic association of the features mentioned above. Furthermore, it is important that whenever such cases are identified termination of pregnancy should be considered. The article also underscores the importance of fetal autopsies.

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Authors and Affiliations

  1. Department of Pathology, Dr. Rajendra Prasad Government Medical College, Kangra, Tanda, Himachal Pradesh, 176001, India

    Bal Chander

  2. Department of Anatomy, Dr. Rajendra Prasad Government Medical College, Kangra, Tanda, India

    Daisy Dwivedi & Suman Yadav

  3. Department of Obstetrics and Gynecology, Dr. Rajendra Prasad Government Medical College, Kangra, Tanda, India

    Sita Thakur

Authors
  1. Bal Chander
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  2. Daisy Dwivedi
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  3. Sita Thakur
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  4. Suman Yadav
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Correspondence to Bal Chander.

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There is no conflict of interest. Furthermore the study was not funded by any organization.

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Ethical approval was taken from Institutional ethical committee. We in Dr Rajendra Prasad Government Medical College regularly perform fetal autopsies.

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Chander, B., Dwivedi, D., Thakur, S. et al. Placento-Cranial Adhesion: A New Syndromic Association. J. Fetal Med. 6, 51–56 (2019). https://doi.org/10.1007/s40556-019-00203-z

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  • DOI: https://doi.org/10.1007/s40556-019-00203-z

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